Signs and symptoms of hemolytic uremic syndrome may include:
- Bloody diarrhea
- Abdominal pain
- Pale skin tone
- Fatigue and irritability
- Fever, usually not high and may not be present at all
- Blood in the urine
- Small, unexplained bruises or bleeding from the nose and mouth
- Decreased urination or blood in the urine
- Swelling of the face, hands, feet or entire body
Sometimes neurological symptoms, such as seizures, develop as well.
When to see a doctor
Call your doctor immediately if you or your child experiences unexplained bruises, bloody diarrhea, unusual bleeding, swollen limbs, extreme fatigue or decreased urine output after several days of diarrhea. Seek emergency care if you or your child doesn't urinate for 12 hours or more.
Jul. 03, 2013
- Niaudet P. Clinical manifestations and diagnosis of Shiga toxin associated (typical) hemolytic uremic syndrome in children. http://www.uptodate.com/home. Accessed May 26, 2013.
- Tintinalli JE, et al. Tintinalli's Emergency Medicine: A Comprehensive Study Guide. 7th ed. New York, N.Y.: The McGraw-Hill Companies; 2011. http://www.accessmedicine.com/resourceTOC.aspx?resourceID=40. Accessed May 26, 2013.
- Bavaro MF. E. coli O157:H7 and other toxigenic strains: The curse of global food distribution. Current Gastroenterology Reports. 2012;14:317.
- Thrombotic thrombocytopenic purpura (TTP) and hemolytic-uremic syndrome. The Merck Manuals: The Merck Manual for Healthcare Professionals. http://www.merck.com/mmpe/print/sec11/ch133/ch133g.html. Accessed May 26, 2013.
- Hemolytic uremic syndrome in children. National Kidney and Urologic Diseases Information Clearinghouse . http://kidney.niddk.nih.gov/KUDiseases/pubs/childkidneydiseases/hemolytic_uremic_syndrome/. Accessed May 21, 2013.
- Bielaszewska M, et al. Enterohemorrhagic escherichia coli O26:H11/H-: A new virulent clone emerges in Europe. Clinical Infectious Diseases. 2013;56:1373.
- George JN. Causes of thrombotic thrombocytopenic purpura-hemolytic uremic syndrome in adults. http://www.uptodate.com/home. Accessed May 26, 2013.
- Elliott MM, et al. Interventions for haemolytic uraemic syndrome and thrombotic thrombocytopenic purpura. Cochrane Database of Systematic Reviews. http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD003595.pub2/abstract. Accessed May 26, 2013.
- Food safety. Centers for Disease Control and Prevention. http://www.cdc.gov/foodsafety/facts.html. Accessed May 26, 2013.
- Niaudet P. Treatment and prognosis of Shiga toxin associated (typical) hemolytic uremic syndrome in children. http://www.uptodate.com/home. Accessed May 26, 2013.
- Niaudet P. Atypical hemolytic uremic syndrome in children. http://www.uptodate.com/home. Accessed May 26, 2013.
- Nester CM, et al. Atypical hemolytic uremic syndrome: What is it, how is it diagnosed, and how is it treated? Hematology. 2012;2012:617.
- Ground beef and food safety. U.S. Department of Agriculture. http://www.fsis.usda.gov/factsheets/ground_beef_and_food_safety/. Accessed May 28, 2013.
- Hunt JM. Shiga toxin-producing Escherichia coli (STEC). Clinics in Laboratory Medicine. 2010;30:21.
You Are ... The Campaign for Mayo Clinic
Mayo Clinic is a not-for-profit organization. Make a difference today.