DefinitionBy Mayo Clinic Staff
Graves' disease is an immune system disorder that results in the overproduction of thyroid hormones (hyperthyroidism). Although a number of disorders may result in hyperthyroidism, Graves' disease is a common cause.
Because thyroid hormones affect a number of different body systems, signs and symptoms associated with Graves' disease can be wide ranging and significantly influence your overall well-being. Although Graves' disease may affect anyone, it's more common among women and before the age of 40.
The primary treatment goals are to inhibit the overproduction of thyroid hormones and lessen the severity of symptoms.
July 01, 2014
- Bartalena L. Diagnosis and management of Graves disease: A global overview. Nature Reviews Endocrinology. 2013;9:724.
- Graves' disease. U.S. Department of Health and Human Services. http://www.endocrine.niddk.nih.gov/pubs/graves/index.aspx. Accessed March 9, 2014.
- Longo DL, et al. Harrison's Online. 18th ed. New York, N.Y.: The McGraw-Hill Companies; 2012. http://www.accessmedicine.com/resourceTOC.aspx?resourceID=4. Accessed March 9, 2014.
- Papadakis MA, ed., et al. Current Medical Diagnosis & Treatment 2014. 53rd ed. New York, N.Y.: The McGraw-Hill Companies; 2014. http://www.accessmedicine.com/resourceTOC.aspx?resourceID=1. Accessed March 9, 2014.
- Falgarone G, et al. Role of emotional stress in the pathophysiology of Graves' disease. European Journal of Endocrinology. 2013;168:R13.
- Ross DS. Treatment of Graves' hyperthyroidism. http://www.uptodate.com/home. Accessed March 9, 2014.
- Genovese BM, et al. What is the best definitive treatment for Graves' disease? A systematic review of the existing literature. Annals of Surgical Oncology. 2013;20:660.
- Mayo CH. The surgical treatment of goiter. The Journal of the American Medical Association. 1904;XLII:1059.
- Riggin EA. Decision Support System. Mayo Clinic, Rochester, Minn. March 3, 2014.