People with gout can develop more-severe conditions, such as:
Nov. 25, 2014
- Recurrent gout. Some people may never experience gout signs and symptoms again. But others may experience gout several times each year. Medications may help prevent gout attacks in people with recurrent gout. If left untreated, gout can cause erosion and destruction of a joint.
- Advanced gout. Untreated gout may cause deposits of urate crystals to form under the skin in nodules called tophi (TOE-fie). Tophi can develop in several areas such as your fingers, hands, feet, elbows or Achilles tendons along the backs of your ankles. Tophi usually aren't painful, but they can become swollen and tender during gout attacks.
- Kidney stones. Urate crystals may collect in the urinary tract of people with gout, causing kidney stones. Medications can help reduce the risk of kidney stones.
- Hochberg MC, et al. Rheumatology. 6th ed. Philadelphia, Pa.: Mosby Elsevier; 2015. http://www.clinicalkey.com. Accessed Oct. 20, 2014.
- Pluta RM, et al. Gout. The Journal of the American Medical Association. 2010;304:2314.
- Ferri FF. Ferri's Clinical Advisor 2015: 5 Books in 1. Philadelphia, Pa.: Mosby Elsevier; 2015. https://www.clinicalkey.com. Accessed Oct. 20, 2014.
- Gout. American College of Rheumatology. http://www.rheumatology.org/Practice/Clinical/Patients/Diseases_And_Conditions/Gout/ . Accessed Oct. 20, 2014.
- Questions and answers about gout. National Institute of Arthritis and Musculoskeletal and Skin Diseases. http://www.niams.nih.gov/Health_Info/Gout/default.asp. Accessed Oct. 20, 2014.
- Moi JY, et al. Lifestyle interventions for acute gout. Cochrane Database of Systematic Reviews. http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD010519.pub2/abstract. Accessed Oct. 20, 2014.
- Van Derme CG, et al. Non-steroidal anti-inflammatory drugs for acute gout. Cochrane Database of Systematic Reviews. http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD010120.pub2/abstract. Accessed Oct. 20, 2014.
- Becker MA. Treatment of acute gout. http://www.uptodate.com/home. Accessed Oct. 20, 2014.
- Becker MA. Prevention of recurrent gout. http://www.uptodate.com/home. Accessed Oct. 20, 2014.
- Gout. Natural Medicines Comprehensive Database. http://www.naturaldatabase.com. Accessed Oct. 22, 2014.
- Kolasinski SL. Food, drink and herbs: Alternative therapies and gout. Current Rheumatology Reports. 2014;16:409.
- Khanna D, et al. 2012 American College of Rheumatology guidelines for management of gout. Part 1: Systematic nonpharmacologic and pharmacologic therapeutic approaches to hyperuricemia. Arthritis Care and Research. 2012;64:1431.
- AskMayoExpert. Gout. Rochester, Minn.: Mayo Foundation for Medical Education and Research; 2013.
- Chang-Miller April (expert opinion). Mayo Clinic, Rochester, Minn. Oct. 29, 2014.
You Are ... The Campaign for Mayo Clinic
Mayo Clinic is a not-for-profit organization. Make a difference today.