All types of Gaucher's disease tend to be progressive. Possible complications depend on the type of Gaucher's disease.
Complications of all types
Possible complications of all types of Gaucher's disease include:
- Bone pain, which can become severe and may be associated with fractures.
- A tendency to bleed, which may result in repeated hemorrhaging in the nostrils or nasal cavities, or bruising in the skin (ecchymosis).
- An increased risk of certain cancers. Older people with Gaucher's disease may have an increased likelihood of developing certain types of cancer, particularly multiple myeloma — uncontrolled multiplication of plasma cells.
Complications of type 2
Complications that are more likely to occur in people with type 2 Gaucher's disease often include serious neurological complications, such as:
- Difficulty walking
- Swallowing problems
As these problems progress and become more severe, they can become debilitating and lead to death.
Complications of type 3
People with type 3 Gaucher's disease are more likely to develop calcification of heart valves, which damages the valves and makes it increasingly difficult for them to open fully and function properly.
Jul. 08, 2011
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