Treatment

Treatment of gastritis depends on the specific cause. Acute gastritis caused by nonsteroidal anti-inflammatory drugs or alcohol may be relieved by stopping use of those substances.

Medications used to treat gastritis include:

  • Antibiotic medications to kill H. pylori. For H. pylori in your digestive tract, your doctor may recommend a combination of antibiotics, such as clarithromycin (Biaxin) and amoxicillin (Amoxil, Augmentin, others) or metronidazole (Flagyl), to kill the bacterium. Be sure to take the full antibiotic prescription, usually for seven to 14 days.
  • Medications that block acid production and promote healing. Proton pump inhibitors reduce acid by blocking the action of the parts of cells that produce acid. These drugs include the prescription and over-the-counter medications omeprazole (Prilosec), lansoprazole (Prevacid), rabeprazole (Aciphex), esomeprazole (Nexium), dexlansoprazole (Dexilant) and pantoprazole (Protonix).

    Long-term use of proton pump inhibitors, particularly at high doses, may increase your risk of hip, wrist and spine fractures. Ask your doctor whether a calcium supplement may reduce this risk.

  • Medications to reduce acid production. Acid blockers — also called histamine (H-2) blockers — reduce the amount of acid released into your digestive tract, which relieves gastritis pain and encourages healing. Available by prescription or over-the-counter, acid blockers include ranitidine (Zantac), famotidine (Pepcid), cimetidine (Tagamet HB) and nizatidine (Axid AR).
  • Antacids that neutralize stomach acid. Your doctor may include an antacid in your drug regimen. Antacids neutralize existing stomach acid and can provide rapid pain relief. Side effects can include constipation or diarrhea, depending on the main ingredients.
May 18, 2017
References
  1. Overview of gastritis. Merck Manual Professional Version. http://www.merckmanuals.com/professional/gastrointestinal-disorders/gastritis-and-peptic-ulcer-disease/overview-of-gastritis. Accessed Nov. 14, 2016.
  2. Gastritis. National Institute of Diabetes and Digestive and Kidney Diseases. https://www.niddk.nih.gov/health-information/health-topics/digestive-diseases/gastritis/Pages/facts.aspx. Accessed Nov. 14, 2016.
  3. Ferri FF. Gastritis. In: Ferri's Clinical Advisor 2017. Philadelphia, Pa.: Elsevier; 2017. https://www.clinicalkey.com. Accessed Nov. 14, 2016.
  4. Jensen PJ, et al. Acute and chronic gastritis due to Helicobacter pylori. http://www.uptodate.com/home. Accessed Nov. 14, 2016.
  5. American College of Gastroenterology guideline on the management of Helicobacter pylori infection. Bethesda, Md.: American College of Gastroenterology. http://gi.org/guideline/management-of-helicobacter-pylori-infection. Accessed Nov. 14, 2016.
  6. Nordenstedt H, et al. Helicobacter pylori-negative gastritis: Prevalence and risk factors. American Journal of Gastroenterology. 2013;108:65.
  7. Feldman M, et al. Classification and diagnosis of gastritis and gastropathy. http://www.uptodate.com/home. Accessed Nov. 14, 2016.
  8. Vieth M, et al. The diagnosis of gastritis. Diagnostic Histopathology. 2014;20:6.
  9. FDA drug safety communication: Possible increased risk of fractures of the hip, wrist and spine with the use of proton pump inhibitors. U.S. Food and Drug Administration. http://www.fda.gov/Drugs/DrugSafety/PostmarketDrugSafetyInformationforPatientsandProviders/ucm213206.htm. Accessed Nov. 18, 2016.
  10. Rajan E (expert opinion). Mayo Clinic, Rochester, Minn. Nov. 23, 2016.