Factors that increase your risk of gastritis include:
May. 14, 2014
- Bacterial infection. Although infection with Helicobacter pylori is among the most common worldwide human infections, only some infected people develop gastritis or a similar stomach disorder. Doctors believe vulnerability to the bacterium could be inherited or could be caused by lifestyle choices, such as smoking and high stress levels.
- Regular use of pain relievers. Common pain relievers — such as aspirin, ibuprofen (Advil, Motrin IB, others) and naproxen (Aleve, Anaprox) — can cause both acute gastritis and chronic gastritis. Using these pain relievers regularly or taking too much of these drugs may reduce a key substance that helps preserve the protective lining of your stomach. Stomach problems are less likely to develop if you take pain relievers only occasionally. Acetaminophen (Tylenol, others) does not lead to gastritis.
- Older age. Older adults have an increased risk of gastritis because the stomach lining tends to thin with age and because older adults are more likely to have H. pylori infection or autoimmune disorders than younger people are.
- Excessive alcohol use. Alcohol can irritate your stomach lining, which makes your stomach more likely to be harmed by digestive juices. Excessive alcohol use is more likely to cause acute gastritis.
- Stress. Severe stress due to major surgery, injury, burns or severe infections can cause acute gastritis.
- Your own body attacking cells in your stomach. Called autoimmune gastritis, this type of gastritis occurs when your body attacks the cells that make up your stomach lining. This produces a reaction by your immune system that can wear away at your stomach's protective barrier. Autoimmune gastritis is more common in people with other autoimmune disorders, including Hashimoto's disease and type 1 diabetes. Autoimmune gastritis can also be associated with vitamin B-12 deficiency.
- Other diseases and conditions. Gastritis may be associated with other medical conditions, including HIV/AIDS, Crohn's disease and parasitic infections.
- Dickson BA, et al. Classification and diagnosis of gastritis and gastropathy. http://www.uptodate.com/home. Accessed Nov. 3, 2013.
- American College of Gastroenterology guideline on the management of Helicobacter pylori infection. Bethesda, Md.: American College of Gastroenterology. http://gi.org/guideline/management-of-helicobacter-pylori-infection. Accessed Nov. 3, 2013.
- Gastritis. National Institute of Diabetes and Digestive and Kidney Diseases. http://digestive.niddk.nih.gov/ddiseases/pubs/gastritis/index.htm. Accessed Nov. 3, 2013.
- Guidelines for the management of dyspepsia. Bethesda, Md.: American College of Gastroenterology. http://gi.org/guideline/management-of-dyspepsia/. Accessed Nov. 3, 2013.
- Jensen PJ, et al. Acute and chronic gastritis due to Helicobacter pylori. http://www.uptodate.com/home. Accessed Nov. 3, 2013.
- H. pylori and peptic ulcers. National Institute of Diabetes and Digestive and Kidney Diseases. http://digestive.niddk.nih.gov/ddiseases/pubs/hpylori/index.htm. Accessed Nov. 3, 2013.
- Mapel D, et al. The epidemiology, diagnosis, and cost of dyspepsia and Helicobacter pylori gastritis: A case-control analysis in the southwestern United States. Helicobacter. 2013;18:54.
- FDA drug safety communication: Possible increased risk of fractures of the hip, wrist and spine with the use of proton pump inhibitors. U.S. Food and Drug Administration. http://www.fda.gov/Drugs/DrugSafety/PostmarketDrugSafetyInformationforPatientsandProviders/ucm213206.htm. Accessed Nov. 3, 2013.
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