Fuchs' dystrophy

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Displaying 1-2 out of 2 doctors available

  1. Darby D. Miller, M.D., M.P.H.

    Darby D. Miller, M.D., M.P.H.

    1. Ophthalmologist
    1. Jacksonville, FL
    Areas of focus:

    LASIK eye surgery, Cataract surgery, Cornea transplant, Laser eye surgery, Photorefractive keratectomy, Keratoconus, Ca...taract, Fuchs' dystrophy, Cornea problems

  2. Sanjay V. Patel, M.D.

    Sanjay V. Patel, M.D.

    1. Ophthalmologist
    1. Rochester, MN
    Areas of focus:

    Cataract surgery, Ocular surface reconstruction, Cornea transplant, Tumor resection, Lens replacement surgery, Photothe...rapeutic keratectomy, Iris prosthesis implantation, Keratoconus, Cataract, Fuchs' dystrophy, Pterygium, Conjunctival melanoma, Ocular surface tumor, Corneal edema, Ocular surface squamous neoplasia, Iris defect

Research

Mayo Clinic's Department of Ophthalmology has a strong tradition of advanced research to improve the diagnosis and treatment of cornea disorders, and is a leader in Fuchs' dystrophy research, from genetics of the disease to clinical management.

The common form of Fuchs' dystrophy begins in the 30s and 40s and accounts for the vast majority of cases in the United States. Mayo Clinic researchers discovered that 75% of these cases were associated with a specific genetic abnormality, a trinucleotide expansion repeat in a gene called transcription factor 4 (TCF4). Researchers at Mayo Clinic and elsewhere are now using this information to discover medical therapies that might slow or stop the progression of the disease. Mayo Clinic researchers have also described how to best use imaging techniques to help manage the disease in clinical practice, and to predict the prognosis of the disease.

Learn more about ongoing clinical trials at Mayo Clinic for people with Fuchs' dystrophy.

Publications

See a list of publications by Mayo Clinic authors on Fuchs' dystrophy on PubMed, a service of the National Library of Medicine.

Research Profiles

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By Mayo Clinic Staff

Fuchs' dystrophy care at Mayo Clinic

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Diagnosis & treatmentCare at Mayo Clinic
March 05, 2022
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Fuchs' dystrophy

Research: It's all about patients

[MUSIC PLAYING]

Joseph Sirven, M.D., Professor of Neurology, Mayo Clinic: Mayo's mission is about the patient. The patient comes first. So the mission and research here is to advance how we can best help the patient, how to make sure the patient comes first in care. So in many ways, it's a cycle. It can start with as simple as an idea worked on in a laboratory, brought to the patient bedside, and if everything goes right — and let's say it's helpful or beneficial — then brought on as a standard approach. And I think that is one of the unique characteristics of Mayo's approach to research — that patient-centeredness — that really helps to put it in its own spotlight.