You may undergo tests such as the following so that your doctor can determine whether you have Fuchs' dystrophy. These tests will also measure the shape, clarity and thickness of the cornea.
Jul. 22, 2014
- Visual test. You'll be asked to read letters and numbers on a chart to measure how well you see at various distances. This is called a visual acuity test and is a routine part of eye exams.
- Staging. Your doctor will try to determine the stage of your condition by examining your eye with an optical microscope (slit lamp). He or she will then study the cells lining the back surface of your cornea (endothelial cells). If you have irregular bumps (guttae) on the back surface of the cornea, you may have Fuchs' dystrophy.
- Corneal pressure test. Your doctor may numb your eyes with drops and then briefly touch your eye with a special instrument that measures eye pressure.
- Corneal thickness. Your doctor may use a special instrument to measure the thickness of the cornea.
- Corneal cell count. Sometimes your doctor might use another special instrument to record the number, shape and size of the cells that line the back of the cornea.
- Facts about the cornea and corneal disease. National Eye Institute. http://www.nei.nih.gov/health/cornealdisease. Accessed Feb. 7, 2014.
- What is Fuchs' dystrophy? American Academy of Ophthalmology. http://www.geteyesmart.org/eyesmart/diseases/fuchs-dystrophy.cfm. Accessed Feb. 7, 2014.
- Patel SV, et al. Anterior corneal aberrations after Descemet's stripping endothelial keratoplasty for Fuchs' endothelial dystrophy. Ophthalmology. 2012;119:1522.
- Gipson IK. Age-related changes and diseases of the ocular surface and cornea. Investigative ophthalmology and visual science. 2013;54:ORSF48.
- Hamill CE, et al. Fuchs endothelial cornea dystrophy: A review of the genetics behind disease development. Seminars in Ophthalmology. 2013;28:281.
- Riggin EA. Decision Support System. Mayo Clinic, Rochester, Minn. Feb. 10, 2014.
- Wieben ED, et al. A common trinucleotide repeat expansion within the transcription factor 4 (TCF4, E2-2) gene predicts Fuchs corneal dystrophy. PLoS One. 2012;7:e49083. http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0049083. Accessed Feb. 13, 2014.
- What is a comprehensive dilated eye exam? National Eye Institute. http://www.nei.nih.gov/healthyeyes/eyeexam.asp. Accessed Feb. 24, 2014.
- The Wills Eye Manual: Office and Emergency Room Diagnosis and Treatment of Eye Disease Gerstenblith AT, et al., eds. Disease. 6th ed. Philadelphia, Pa.: Wolters Kluwer Health Lippincott Williams & Wilkins; 2012. http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=booktext&D=books3&AN=01626623/6th_Edition/2&XPATH=/OVIDBOOK%5b1%5d/METADATA%5b1%5d/TBY%5b1%5d/EDITORS%5b1%5d. Accessed Feb. 24, 2014.
- Robertson DM (expert opinion). Mayo Clinic, Rochester, Minn. March 5, 2014.
- Patel SV. Graft survival and endothelial outcomes in the new era of endothelial keratoplasty. Experimental Eye Research. 2012; 95:40.
- Patel SV (expert opinion). Mayo Clinic, Rochester, Minn. May 20, 2014.
- Baratz KH, et al. E2-2 protein and Fuchs's corneal dystrophy. New England Journal of Medicine. 2010;363:1016.
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