Fibrous dysplasia is an uncommon bone disorder in which scar-like (fibrous) tissue develops in place of normal bone. This irregular tissue can weaken the affected bone and cause it to deform or fracture.
In most cases, fibrous dysplasia occurs at a single site in one bone, but can occur at multiple sites in multiple bones. Single bone involvement usually occurs in adolescents and young adults. People who have more than one affected bone typically develop symptoms before the age of 10.
Although fibrous dysplasia is a genetic disorder, it's caused by a gene mutation that's not passed from parent to child. There's no cure for the disorder. Treatment, which may include surgery, focuses on relieving pain and repairing or stabilizing bones.
July 14, 2017
- Fibrous dysplasia. American Academy of Orthopaedic Surgeons. http://orthoinfo.aaos.org/topic.cfm?topic=A00083. Accessed May 13, 2017.
- Hakim DN, et al. Benign tumours of the bone: A review. Journal of Bone Oncology. 2015;4:37.
- Czerniak B. Fibrous dysplasia and related lesions. In: Dorfman and Czerniak's Bone Tumors. Philadelpia, Pa.: Saunders Elsevier; 2016. https://www.clinicalkey.com. Accessed May 12, 2017.
- Tis JE. Benign bone tumors in children and adolescents. https://www.uptodate.com/home. Accessed May 12, 2017.
- Fibrous dysplasia overview. National Institute of Arthritis and Musculoskeletal and Skin Diseases. https://www.niams.nih.gov/Health_Info/Bone/Additional_Bone_Topics/fibrous_dysplasia.asp. Accesssed May 12, 2017.