Many factors might increase the risk of fetal macrosomia — some you can control, but others you can't.
Maternal diabetes. If you had diabetes before pregnancy (pre-gestational diabetes) or you develop diabetes during pregnancy (gestational diabetes), fetal macrosomia is more likely.
If your diabetes is poorly controlled, your baby is likely to have larger shoulders and greater amounts of body fat than would a baby whose mother doesn't have diabetes.
- A history of fetal macrosomia. If you've previously given birth to a baby diagnosed with fetal macrosomia, you're at increased risk of having another baby who has the condition. Also, if you weighed more than 8 pounds, 13 ounces at birth, you're more likely to have a large baby.
- Maternal obesity. Fetal macrosomia is more likely if you're obese.
- Excessive weight gain during pregnancy. Gaining too much weight during pregnancy increases the risk of fetal macrosomia.
- Previous pregnancies. The risk of fetal macrosomia increases with each pregnancy. Up to the fifth pregnancy, the average birth weight for each successive pregnancy typically increases by up to about 4 ounces (113 grams).
- You're having a boy. Male infants typically weigh slightly more than female infants. Most babies who weigh more than 9 pounds, 15 ounces (4,500 grams) are male.
- Overdue pregnancy. If your pregnancy continues by more than two weeks past your due date, your baby is at increased risk of fetal macrosomia.
- Maternal age. Women older than 35 are more likely to have a baby diagnosed with fetal macrosomia.
Fetal macrosomia is more likely to be a result of maternal diabetes, obesity or weight gain during pregnancy than other causes. If these risk factors aren't present and fetal macrosomia is suspected, it's possible that your baby might have a rare medical condition that affects fetal growth.
Your health care provider might recommend prenatal diagnostic tests and perhaps a visit with a genetic counselor, depending on the test results.
April 16, 2015
- Copel JA, et al. Fetal macrosomia. In: Obstetric Imaging. Philadelphia, Pa.: Saunders Elsevier; 2012. http://www.clinicalkey.com. Accessed Feb. 8, 2015.
- Allen K, et al. Fetal macrosomia. Obstetrics, Gynaecology and Reproductive Medicine. 2013;23:6.
- Chatfield J. ACOG issues guidelines on fetal macrosomia. American Family Physician. 2001;64:169.
- Abramocwicz JS, et al. Fetal macrosomia. http://www.uptodate.com/home. Accessed Feb. 8, 2015.
- Vendittelli F, et al. Is prenatal identification of fetal macrosomia useful? European Journal of Obstetrics & Gynecology and Reproductive Biology. 2012;161:170.
- Negrato CA, et al. Adverse pregnancy outcomes in women with diabetes. 2012;4:41.
- Frequently asked questions. Pregnancy FAQ098. Special tests for monitoring fetal health. American Congress of Obstetricians and Gynecologists. http://www.acog.org/Patients/FAQs/Special-Tests-for-Monitoring-Fetal-Health . Accessed Feb. 10, 2015.
- Koyanagi A, et al. Macrosomia in 23 developing countries: An analysis of a multicountry, facility-based, cross-sectional survey. The Lancet. 2013:381:476.
- Lim CC, et al. Obesity in pregnancy. Best Practice & Research Clinical Obstetrics and Gynaecology. In press. Accessed Feb. 8, 2015.
- Routine prenatal care. Bloomington, Minn.: Institute for Clinical Systems Improvement. https://www.icsi.org/guidelines__more/. Accessed Feb. 8, 2015.
- American College of Obstetricians and Gynecologists (ACOG) Committee on Practice Bulletins — Obstetrics. ACOG Practice Bulletin No. 22: Fetal macrosomia. Obstetrics & Gynecology. 2000;96:1.
- Wick MJ (expert opinion). Mayo Clinic, Rochester, Minn. Feb. 12, 2015.
- Manning FA. The fetal biophysical profile. http://www.uptodate.com/home. Accessed Feb. 12, 2015.
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