A family history of factor V Leiden increases your risk of inheriting the disorder. The disorder is most common in people who are white and of European descent.

Risk factors that can increase your risks of developing complications, such as a DVT, include:

  • Being pregnant
  • Taking birth control pills or hormone replacement therapy
  • Taking medications to treat breast cancer or prevent a recurrence of breast cancer, called selective estrogen receptor modulators (SERMS), such as tamoxifen and raloxifene (Evista)
  • Being over age 60
  • Being overweight or obese
  • Getting a leg injury
  • Having surgery or other invasive medical procedures
  • Traveling for more than a few hours, especially by airplane
Sept. 06, 2012