Tests and diagnosis

By Mayo Clinic Staff

Your doctor may suspect epidermolysis bullosa from the appearance of the skin, but laboratory tests are needed to confirm the diagnosis. They include:

  • Skin biopsy. Removing a small sample of affected skin and examining it under a microscope can reveal which layer of skin is separating and which type of epidermolysis bullosa is present. Sometimes very specialized tests, such as electron microscopy or immunoelectron microscopy, are required to confirm the diagnosis.
  • Genetic testing. Because most forms of epidermolysis bullosa are inherited, the results of genetic testing, usually done with a blood sample sent to a lab for analysis, can confirm the diagnosis.
Sep. 27, 2011

You Are ... The Campaign for Mayo Clinic

Mayo Clinic is a not-for-profit organization. Make a difference today.