Overview

Emphysema is a lung condition that causes shortness of breath. In people with emphysema, the air sacs in the lungs (alveoli) are damaged. Over time, the inner walls of the air sacs weaken and rupture — creating larger air spaces instead of many small ones. This reduces the surface area of the lungs and, in turn, the amount of oxygen that reaches your bloodstream.

When you exhale, the damaged alveoli don't work properly and old air becomes trapped, leaving no room for fresh, oxygen-rich air to enter.

Most people with emphysema also have chronic bronchitis. Chronic bronchitis is inflammation of the tubes that carry air to your lungs (bronchial tubes), which leads to a persistent cough.

Emphysema and chronic bronchitis are two conditions that make up chronic obstructive pulmonary disease (COPD). Smoking is the leading cause of COPD. Treatment may slow the progression of COPD, but it can't reverse the damage.

April 28, 2017
References
  1. What is COPD? National Heart, Lung, and Blood Institute. https://www.nhlbi.nih.gov/health/health-topics/topics/copd/#. Accessed Jan. 9, 2017.
  2. Mason RJ, et al. COPD: Pathogenesis and natural history. In: Murray and Nadel's Textbook of Respiratory Medicine. 6th ed. Philadelphia, Pa.: Saunders Elsevier; 2016. http://www.clinicalkey.com. Accessed Jan. 11, 2017.
  3. Goldman L, et al., eds. Chronic obstructive pulmonary disease. In: Goldman-Cecil Medicine. 25th ed. Philadelphia, Pa.: Saunders Elsevier; 2016. http://www.clinicalkey.com. Accessed Jan. 12, 2017.
  4. AskMayoExpert. Chronic obstructive pulmonary disease. Rochester, Minn.: Mayo Foundation for Medical Education and Research; 2016.
  5. Longo DL, et al., eds. Chronic obstructive pulmonary disease. In: Harrison's Principles of Internal Medicine. 19th ed. New York, N.Y.: McGraw-Hill Education; 2015. http://www.accessmedicine.com. Accessed Jan. 11, 2017.
  6. Weiss ST. Chronic obstructive pulmonary disease: Risk factors and risk reduction. http://www.uptodate.com/home. Accessed Jan. 11, 2017.
  7. Han MK, et al. Chronic obstructive pulmonary disease: Definition, clinical manifestations, diagnosis, and staging. http://www.uptodate.com/home. Accessed Jan. 11, 2017.
  8. Ferguson GT, et al. Management of stable chronic obstructive pulmonary disease. http://www.uptodate.com/home. Accessed Jan. 11, 2017.
  9. What is bronchitis? National Heart, Lung, and Blood Institute. http://www.nhlbi.nih.gov/health/health-topics/topics/brnchi. Accessed Jan. 9, 2017.
  10. Jong EC, et al. Travel with chronic medical conditions. In: Travel and Tropical Medicine Manual. 4th ed. Philadelphia, Pa.: Saunders Elsevier; 2008.
  11. Gautret P, et al. Travel-associated illness in older adults (>60 y). Journal of Travel Medicine. 2012;19:169.
  12. Fishwick D, et al. Occupational chronic obstructive pulmonary disease: A standard of care. Occupational Medicine. 2015;65:270.
  13. Support and community. American Lung Association. http://www.lung.org/support-and-community/. Accessed Jan. 23, 2017.
  14. COPD treatment options. National Heart, Lung, and Blood Institute. https://www.nhlbi.nih.gov/health/educational/copd/breathing-better/treatment-options.htm. Accessed Jan. 23, 2017.