Dupuytren's contracture can make it difficult to perform certain functions using your hand. Since the thumb and index finger aren't usually affected, many people don't experience much inconvenience or disability with fine activities such as writing. But as Dupuytren's contracture progresses, it can limit your ability to fully open your hand and make it difficult to grasp large objects or to get your hand into narrow places.

Oct. 24, 2012