Dressler syndrome

Diagnosis

Diagnosis of Dressler syndrome starts with a physical exam from your healthcare professional. The exams includes listening to the heart with a device called a stethoscope. A sound called a pericardial rub can happen when the pericardium is inflamed or when fluid has collected around the heart.

Tests that can help find out if you have Dressler syndrome include:

• Complete blood count. Most people with Dressler syndrome have an increased white blood cell count.
• Blood tests to measure inflammation. A blood test can check the level of C-reactive protein made by the liver. A higher level of this protein can be a sign of inflammation that's linked with Dressler syndrome. Another blood test called erythrocyte sedimentation rate measures how fast red blood cells sink to the bottom of a test tube. When they sink fast, it can be a sign of more inflammation.
• Electrocardiogram (ECG or EKG). This quick test checks the electrical activity of the heart. It shows how the heart is beating. Sticky patches called electrodes attach to the chest and sometimes the arms and legs. Wires connect the electrodes to a computer that prints or displays the test results. Certain changes in the heart's electrical signals can be a sign of pressure on the heart. But these changes can happen after heart surgery, so the results of other tests are needed to confirm whether you have Dressler syndrome.
• Chest X-ray. A chest X-ray can help detect fluid around the heart or lungs. It also can help find out if the fluid is caused by a different condition, such as pneumonia.
• Echocardiogram. Sound waves make an image of the heart to show if fluid is collecting around it.
• Cardiac MRI. This test uses sound waves to create still or moving pictures of how blood flows through the heart. This test can show thickening of the pericardium.

Treatment

The goals of treatment for Dressler syndrome are to manage pain and lower the inflammation. Treatment may involve medicines. Surgery may be needed if complications happen.

Medications

The main treatment for Dressler syndrome is medicine to lower inflammation, including nonsteroidal anti-inflammatory drugs (NSAIDs) such as:

• Aspirin.
• Ibuprofen (Advil, Motrin IB, others).
• Colchicine (Colcrys, Gloperba, others).

If Dressler syndrome happens after a heart attack, usually aspirin is preferred over other NSAIDs.

Indomethacin also may be given.

If those medicines don't help, the next step might be corticosteroids. These can lower inflammation linked with Dressler syndrome by turning down the immune system.

Corticosteroids can have serious side effects. And they might interfere with the healing of damaged heart tissue after a heart attack or surgery. For those reasons, corticosteroids tend to be used only when other treatments don't work.

Surgery or other procedures

Other treatments may be needed to treat complications of Dressler syndrome. These include:

• Draining excess fluids. For cardiac tamponade, the excess fluid can be removed with a needle or a small tube called a catheter. This treatment is called pericardiocentesis. It's usually done using medicine called a local anesthetic that numbs a specific part of the body.
• Removing the pericardium. For constrictive pericarditis, treatment might involve surgery to remove the pericardium. The surgery is called pericardiectomy.

Preparing for your appointment

If you're being seen in the emergency room for chest pain, you might be asked:

• When did your symptoms begin?
• How bad is your chest pain on a scale of 1 to 10?
• Does anything make your symptoms worse? For example, does it hurt more when you take a deep breath?
• Where is the pain? Does it go anywhere beyond your chest?
• Have you recently had a heart attack, heart surgery or blunt trauma to your chest?
• Do you have a history of heart disease?
• What medicines do you take?