Self-management

Coping and support

Having a child with DiGeorge syndrome (22q11.2 deletion syndrome) is challenging. You must deal with numerous treatment issues, manage your own expectations and meet the needs of your child. Ask your health care team about organizations that provide educational materials, support groups and other resources for parents of children with 22q11.2 deletion syndrome.

Prevention

In some cases, DiGeorge syndrome (22q11.2 deletion syndrome) may be passed from an affected parent to a child. If you're concerned about a family history of 22q11.2 deletion syndrome, or if you already have a child with the syndrome, you may want to consult a doctor who specializes in genetic disorders (geneticist) or a genetic counselor for help in planning future pregnancies.

July 18, 2017
References
  1. National Library of Medicine. 22q11.2 deletion syndrome. Genetics Home Reference. https://ghr.nlm.nih.gov/condition/22q112-deletion-syndrome#genes. Accessed May 25, 2017.
  2. 22q11.2 deletion disorders (DiGeorge syndrome and velocardiofacial syndrome). American Heart Association. http://www.heart.org/HEARTORG/Conditions/CongenitalHeartDefects/AboutCongenitalHeartDefects/22q112-Deletion-Disorders-DiGeorge-Syndrome-and-Velocardiofacial-Syndrome_UCM_309017_Article.jsp#.WSc5wWd1rRE. Accessed May 25, 2017.
  3. DiGeorge syndrome (DGS). American Academy of Allergy Asthma & Immunology. http://www.aaaai.org/conditions-and-treatments/primary-immunodeficiency-disease/digeorge-syndrome. Accessed May 25, 2017.
  4. DiGeorge syndrome. Merck Manual Professional Version. https://www.merckmanuals.com/professional/immunology-allergic-disorders/immunodeficiency-disorders/digeorge-syndrome. Accessed May 25, 2017.
  5. Hofstetter AM, et al. Live vaccine use and safety in DiGeorge syndrome. Pediatrics. 2014;133:e946.
  6. Chromosome 22q11.2 deletion syndrome. National Organization for Rare Disorders. https://rarediseases.org/rare-diseases/chromosome-22q11-2-deletion-syndrome/. Accessed May 25, 2017.
  7. Seroogy CM. DiGeorge (22q11.2 deletion) syndrome: Epidemiology and pathogenesis. https://www.uptodate.com/contents/search. Accessed May 25, 2017.
  8. Seroogy CM. DiGeorge (22q11.2 deletion) syndrome: Clinical features and diagnosis. https://www.uptodate.com/contents/search. Accessed May 25, 2017.
  9. Seroogy CM. DiGeorge (22q11.2 deletion) syndrome: Management and prognosis. https://www.uptodate.com/contents/search. Accessed May 25, 2017.
  10. AskMayoExpert. 22q11.2 deletion syndrome. Rochester, Minn.: Mayo Foundation for Medical Education and Research; 2016. Accessed May 10, 2017.
  11. Babovic-Vuksanovic D (expert opinion). Mayo Clinic, Rochester, Minn. July 6, 2017.