Proximal neuropathy (diabetic amyotrophy)
Instead of affecting the ends of nerves in the feet, legs, hands and arms, like peripheral neuropathy, proximal neuropathy affects nerves in the thighs, hips, buttocks or legs. Also called diabetic amyotrophy or radiculoplexus neuropathy, this condition is more common in people with type 2 diabetes and older adults.
Symptoms are usually on one side of the body, though in some cases symptoms may spread to the other side, too. Most people improve at least partially over 6 to 12 months. This condition is often marked by:
- Sudden, severe pain in your hip and thigh or buttock
- Weakness and atrophy of the thigh muscles
- Difficulty rising from a sitting position
Mononeuropathy involves damage to a specific nerve. The nerve may be in the face, torso or leg. Mononeuropathy, which may also be called focal neuropathy, often comes on suddenly. It's most common in older adults.
Although mononeuropathy can cause severe pain, it usually doesn't cause any long-term problems. Symptoms usually diminish and disappear on their own over a few weeks or months. Signs and symptoms depend on which nerve is involved, and may include:
- Difficulty focusing your eyes, double vision or aching behind one eye
- Paralysis on one side of your face (Bell's palsy)
- Pain in your shin or foot
- Pain in the front of your thigh
- Chest or abdominal pain
Sometimes mononeuropathy occurs when a nerve is compressed. Carpal tunnel syndrome is a common type of compression neuropathy in people with diabetes.
Signs and symptoms of carpal tunnel syndrome include:
- Numbness or tingling in your fingers or hand, especially in your thumb, index finger, middle finger and ring finger
- A sense of weakness in your hand and a tendency to drop things
Be sure to discuss any neuropathy symptoms with your doctor. Early diagnosis and treatment offer the best chance for controlling symptoms and preventing more-severe problems.
May 17, 2017
See more In-depth
- Nerve damage (Diabetic neuropathies). National Institute of Diabetes and Digestive and Kidney Diseases. https://www.niddk.nih.gov/health-information/diabetes/overview/preventing-problems/nerve-damage-diabetic-neuropathies. Accessed March 1, 2017.
- Longo DL, et al., eds. Diabetes mellitus: Complications. In: Harrison's Principles of Internal Medicine. 19th ed. New York, N.Y.: McGraw-Hill Education; 2015. http://accessmedicine.com. Accessed March 3, 2017.
- Melmed S, et al. Complications of diabetes mellitus. In: Williams Textbook of Endocrinology. 13th ed. Philadelphia, Pa.: Elsevier; 2016. https://www.clinicalkey.com. Accessed March 1, 2017.
- Feldman EL. Clinical manifestations and diagnosis of diabetic polyneuropathy. http://www.uptodate.com/home. Accessed Feb. 27, 2017.
- Shefner JM. Diabetic autonomic neuropathy. http://www.uptodate.com/home. Accessed Feb. 27, 2017.
- Kothari MJ. Carpal tunnel syndrome: Clinical manifestations and diagnosis. http://www.uptodate.com/home. Accessed March 3, 2017.