The most common signs and symptoms of diabetes insipidus are:
- Extreme thirst
- Excretion of an excessive amount of diluted urine
Depending on the severity of the condition, urine output can range from 2 quarts (about 2 liters) a day if you have mild diabetes insipidus to 21 quarts (about 20 liters) a day if the condition is severe and if you're drinking a lot of fluids. In comparison, the average urine output for a healthy adult varies, but is in the range of 1.6 to 2.6 quarts (about 1.5 to 2.5 liters) a day.
Other signs may include needing to get up at night to urinate (nocturia) and bed-wetting.
Infants and young children who have diabetes insipidus may have the following signs and symptoms:
- Unexplained fussiness or inconsolable crying
- Unusually wet diapers
- Fever, vomiting or diarrhea
- Dry skin with cool extremities
- Delayed growth
- Weight loss
When to see a doctor
See your doctor immediately if you notice the two most common signs of diabetes insipidus: excessive urination and extreme thirst.
Mar. 14, 2013
- Diabetes insipidus. National Kidney and Urologic Diseases Information Clearinghouse. http://kidney.niddk.nih.gov/kudiseases/pubs/insipidus/. Accessed Dec. 4, 2012.
- Kronenberg HM, et al. Williams Textbook of Endocrinology. 12th ed. Philadelphia, Pa.: Saunders Elsevier; 2011. http://www.mdconsult.com/das/book/body/191205553-3/0/1555/0.html#. Accessed Dec. 4, 2012.
- Diabetes insipidus. National Institutes of Health Clinical Center. http://www.cc.nih.gov/ccc/patient_education/pepubs/di.pdf. Accessed Dec. 4, 2012.
- Papadakis MA, et al. Current Medical Diagnosis & Treatment 2013. 52nd ed. New York, N.Y.: The McGraw-Hill Companies; 2013. http://www.accessmedicine.com/resourceTOC.aspx?resourceID=1. Accessed Dec. 4, 2012.
- Di Iorgi N, et al. Diabetes insipidus Diagnosis and management. Hormone Research in Paediatrics. 2012;77:69.
- Goldman L, et al. Cecil Medicine. 24th ed. Philadelphia, Pa.: Saunders Elsevier; 2012. http://www.mdconsult.com/das/book/body/191371208-2/0/1492/0.html#. Accessed Dec. 4, 2012.
- Gardner DG, et al. Greenspan's Basic & Clinical Endocrinology. 9th ed. New York, N.Y.: The McGraw-Hill Companies; 2011. http://www.accessmedicine.com/resourceTOC.aspx?resourceID=13. Accessed Dec. 4, 2012.
- Halter JB, et al. Hazzard's Geriatric Medicine and Gerontology. 6th ed. New York, N.Y.: The McGraw-Hill Companies; 2009. http://www.accessmedicine.com/resourceTOC.aspx?resourceID=540. Accessed Dec. 6, 2012.
- Bichet DG. Treatment of nephrogenic diabetes insipidus. http://www.uptodate.com/home/index. Accessed Dec. 6, 2012.
- Nippoldt TB (expert opinion). Mayo Clinic, Rochester, Minn. Dec. 17, 2012.