Treatment options for desmoplastic small round cell tumors include:
May 27, 2014
Surgery. When possible, surgeons work to remove all of the cancer. It's not always possible though, if the tumor has grown to involve nearby structures. In these cases, your doctor may recommend other treatments to shrink the tumor first.
When it's not possible to remove the cancer entirely, your surgeon may work to remove as much of the cancer as possible.
- Chemotherapy. Chemotherapy uses drugs to kill cancer cells. Chemotherapy may be used before surgery to shrink a tumor and make it more likely that it can be successfully removed during an operation. Chemtoherapy may also be used after surgery to kill any cells that might remain after the operation.
- Radiation therapy. Radiation therapy uses powerful energy beams, such as X-rays, to kill cancer cells. Radiation therapy may be recommended after surgery to kill any cancer cells that remain.
- Stem cell transplant. In certain situations, your doctor may recommend a stem cell transplant to replace your bone marrow with bone marrow stem cells from your own body (autologous stem cell transplant). This procedure is also called a bone marrow transplant. High-dose chemotherapy is given before the stem cell infusion.
- Goldblum JR, et al. Enzinger and Weiss's Soft Tissue Tumors. 6th ed. Philadelphia, Pa.: Saunders Elsevier; 2014. http://www.clinicalkey.com. Accessed Feb. 20, 2014.
- Jordan AH, et al. Management of desmoplastic small round-cell tumors in children and young adults. Journal of Pediatric Hematology/Oncology. 2012;34(suppl):S73.
- Arora VC, et al. Characteristic imaging features of desmoplastic small round cell tumour. Pediatric Radiology. 2013;43:93.