If your doctor suspects you have dermatomyositis, he or she might suggest some of the following tests:
June 17, 2014
- Blood analysis. A blood test will let your doctor know if you have elevated levels of muscle enzymes, such as creatine kinase (CK) and aldolase. Increased CK and aldolase levels can indicate muscle damage. A blood test can also detect specific autoantibodies associated with different symptoms of dermatomyositis, which can help in determining the best medication and treatment.
- Chest X-ray. This simple test can check for signs of the type of lung damage that sometimes occurs with dermatomyositis.
- Electromyography. A doctor with specialized training inserts a thin needle electrode through the skin into the muscle to be tested. Electrical activity is measured as you relax or tighten the muscle, and changes in the pattern of electrical activity can confirm a muscle disease. The doctor can determine the distribution of the disease by testing different muscles.
- Magnetic resonance imaging (MRI). A scanner creates cross-sectional images of your muscles from data generated by a powerful magnetic field and radio waves. Unlike a muscle biopsy, an MRI can assess inflammation over a large area of muscle.
- Skin or muscle biopsy. A small piece of skin or muscle is removed for laboratory analysis. A skin sample can confirm the diagnosis of dermatomyositis and rule out other disorders, such as lupus. A muscle biopsy may reveal inflammation in your muscles or other problems, like damage or infection. If the skin biopsy confirms the diagnosis, a muscle biopsy may not be necessary.
- NINDS dermatomyositis information page. National Institute of Neurological Disorders and Stroke. http://www.ninds.nih.gov/disorders/dermatomyositis/dermatomyositis.htm. Accessed March 25, 2014.
- Goldman L, et al. Goldman's Cecil Medicine. 24th ed. Philadelphia, Pa.: Saunders Elsevier; 2012. http://www.clinicalkey.com. Accessed March 25, 2014.
- Imboden JB, et al. Current Rheumatology Diagnosis & Treatment. 3rd ed. New York, N.Y.: The McGraw-Hill Companies; 2013. http://www.accessmedicine.com/resourceTOC.aspx?resourceID=809. Accessed March 25, 2014.
- Oddis CV, et al. Rituximab in the treatment of refractory adult and juvenile dermatomyositis and adult polymyositis: A randomized, placebo-phase trial. Arthritis and Rheumatology. 2013;65:314.
- Miller ML. Diagnosis and differential diagnosis of dermatomyositis and polymyositis in adults. http://www.uptodate.com/home. Accessed March 25, 2014.
- Miller ML, et al. Malignancy in dermatomyositis and polymyositis. http://www.uptodate.com/home. Accessed March 27, 2014.
- Miller ML, et al. Initial treatment of dermatomyositis and polymyositis in adults. http://www.uptodate.com/home. Accessed March 27, 2014.
- Miller ML, et al. Treatment of recurrent and resistant dermatomyositis and polymyositis in adults. http://www.uptodate.com/home. Accessed March 27, 2014.
- Vleugels RA. Management of refractory cutaneous dermatomyositis. http://www.uptodate.com/home. Accessed April 11, 2014.
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