The exact cause of depersonalization-derealization disorder isn't well-understood. However, it appears to be linked to an imbalance of certain brain chemicals called neurotransmitters, which can make a brain vulnerable so that heightened states of stress and fear may lead to the disorder.

Symptoms of depersonalization-derealization disorder may be related to:

  • Childhood trauma, such as verbal or emotional abuse or witnessing domestic violence
  • Growing up with a significantly impaired mentally ill parent
  • Suicide or unexpected death of a close friend or family member
  • Severe stress, such as relationship, financial or work-related problems
  • Severe trauma, such as a car accident
May. 24, 2014

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