The exact cause of depersonalization-derealization disorder isn't well-understood. However, it appears to be linked to an imbalance of certain brain chemicals called neurotransmitters, which can make a brain vulnerable so that heightened states of stress and fear may lead to the disorder.
Symptoms of depersonalization-derealization disorder may be related to:
May 24, 2014
- Childhood trauma, such as verbal or emotional abuse or witnessing domestic violence
- Growing up with a significantly impaired mentally ill parent
- Suicide or unexpected death of a close friend or family member
- Severe stress, such as relationship, financial or work-related problems
- Severe trauma, such as a car accident
- Depersonalization/derealization disorder. In: Diagnostic and Statistical Manual of Mental Disorders DSM-5. 5th ed. Arlington, Va.: American Psychiatric Association; 2013. http://www.psychiatryonline.org. Accessed March 18, 2014.
- Highlights of changes from DSM-IV-TR to DSM-5. American Psychiatric Association. http://www.dsm5.org/Pages/Default.aspx. Accessed March 23. 2013.
- Somer E, et al. Evidence-based treatment for depersonalisation-derealisation disorder (DPRD). BMC Psychology. 2013;1:20.
- Simeon D. Depersonalization derealization disorder: Epidemiology, pathogenesis, clinical manifestations, course, and diagnosis. http://www.uptodate.com/home. Accessed March 24, 2014.
- Simeon D. Treatment of depersonalization derealization disorder. http://www.uptodate.com/home. Accessed March 24, 2014.
- Palmer BA (expert opinion). Mayo Clinic, Rochester, Minn. April 1, 2014.
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