Limited scleroderma, also known as CREST syndrome, is one subtype of scleroderma — a condition whose name means "hardened skin."
The skin changes associated with limited scleroderma typically occur only in the lower arms and legs, below the elbows and knees, and sometimes affect the face and neck. Limited scleroderma can also affect your digestive tract, heart, lungs or kidneys.
The problems caused by limited scleroderma may be minor. Sometimes, however, the disease affects the lungs or heart, with potentially serious results. Limited scleroderma has no known cure. Treatments focus on managing symptoms, preventing serious complications and improving quality of life.
May 18, 2017
- What is scleroderma? Scleroderma Foundation. http://www.scleroderma.org/site/PageNavigator/patients_whatis.html#.WG0T5ZK8zhc. Accessed Jan. 4, 2017.
- Scleroderma. American College of Dermatology. http://www.rheumatology.org/I-Am-A/Patient-Caregiver/Diseases-Conditions/Scleroderma. Accessed Jan. 4, 2017.
- Longo DL, et al., eds. Systemic sclerosis (scleroderma) and related disorders. In: Harrison's Principles of Internal Medicine. 19th ed. New York, N.Y.: McGraw-Hill Education; 2015. http://accessmedicine.com. Accessed Jan. 4, 2017.
- Systemic sclerosis: Diffuse and limited. Scleroderma Foundation. http://www.scleroderma.org/site/Search?query=Systemic+scleroderma,+diffuse+and+limited#.WG0UrpK8zhdv. Accessed Jan. 4, 2017.
- Shah AA, et al. My approach to the treatment of scleroderma. Mayo Clinic Proceedings. 2013;88:377.
- AskMayoExpert. Scleroderma. Rochester, Minn.: Mayo Foundation for Medical Education and Research; 2016.
- Handout on health: Scleroderma. National Institute of Arthritis and Musculoskeletal and Skin Diseases. http://www.niams.nih.gov/Health_Info/Scleroderma/default.asp#3. Accessed Jan. 4, 2017.
- Scleroderma. American Academy of Dermatology. https://www.aad.org/public/diseases/painful-skin-joints/scleroderma#tips. Accessed Jan. 5, 2017.
- Kidneys. Scleroderma Foundation. http://www.scleroderma.org/site/PageServer?pagename=body_kidney#.WHU6eZK8zhc. Accessed Jan. 10, 2017.