Factors that increase the risk of developing cholestasis of pregnancy include:

  • A personal or family history of cholestasis of pregnancy
  • A history of liver disease
  • A twin pregnancy

Some of these factors may have to do with heredity, and all probably have to do with increased levels of pregnancy hormones. After you've had the condition once, the risk of developing it during a subsequent pregnancy is high. About half to two-thirds of women experience recurrence of cholestasis of pregnancy.

Aug. 16, 2014

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