July 23, 2015
Below are current clinical trials.2 studies in Cavernous malformations
(open studies only).
Filter this list of studies by location, status and more.
This study aums to determine whether various markers of vascular stability are predictive of clinical events (intracerebral hemorrhage or focal neurologic deficits). The study will alos determine the prevalence of vitamin D deficiency in patients with cavernous malformation and determine if vitamin D deficiency correlates with presenting classification (Hemorrhage, Focal Neurologic Deficit, Seizure, Asymptomatic state) or natural history (hemorrhage risk).
Investigators are trying to learn more about why cavernous malformations form. In addition, investigators are trying to determine which cavernous malformations might cause future symptoms and which ones may be more benign. To do this, investigators are trying to look at various lifestyle factors, medication use, and other medical problems and how they influence what happens over time
- Mouchtouris N, et al. Management of cerebral cavernous malformations: From diagnosis to treatment. The Scientific World Journal. 2015:1.
- Singer RJ, et al. Vascular malformations of the central nervous system. http://www.uptodate.com/home. Accessed June 8, 2015.
- NINDS cerebral cavernous malformation information page. National Institute of Neurological Disorders and Stroke. http://www.ninds.nih.gov/disorders/cavernous_malformation/cavernous_malformation.htm. Accessed June 8, 2015.
- Moore SA, et al. Long-term natural history of incidentally discovered cavernous malformations in a single-center cohort. Journal of Neurosurgery. 2014;120:1188.
- Riggs EA. Decision Support System. Mayo Clinic, Rochester, Minn. May 18, 2015.
- Moultrie F, et al. Outcome after surgical or conservative management of cerebral cavernous malformations. Neurology. 2014;83:582.
- Brown, Jr. RD (expert opinion). Mayo Clinic, Rochester, Minn. June 10, 2015.