Catatonic schizophrenia and other forms of schizophrenia are brain disorders. Genetics and environment likely both play a role in causing catatonic schizophrenia.
Catatonia is much more commonly associated with other conditions. Some of the health problems that can lead to catatonia include other mood disorders, such as depression and bipolar disorder, and medical conditions that affect the central nervous system.
Doctors don't know why some people with schizophrenia develop catatonic symptoms, but one or more underlying problems with the brain are likely responsible. For example, problems with certain naturally occurring brain chemicals called neurotransmitters appear to play a role. Imaging studies show differences in the brain structure of people with schizophrenia, but the significance of these changes is unclear.
Dec. 17, 2010
- Schizophrenia. In: Diagnostic and Statistical Manual of Mental Disorders DSM-IV-TR. 4th ed. Arlington, Va.: American Psychiatric Association; 2000. http://www.psychiatryonline.com. Accessed Sept. 29, 2010.
- Schizophrenia. Skodol AE, et al. Specific personality disorders. In: Hales RE, et al., eds. The American Psychiatric Publishing Textbook of Psychiatry. 5th ed. Arlington, Va.: American Psychiatric Association; 2008. http://www.psychiatryonline.com. Accessed Sept. 29, 2010.
- Jibson MD. Schizophrenia: Clinical presentation, epidemiology, and pathophysiology. http://www.uptodate.com/home/index.html. Accessed Sept. 29, 2010.
- Gejman PV, et al. The role of genetics in the etiology of schizophrenia. Psychiatric Clinics of North America. 2010;33:3.
- Schizophrenia. National Institute of Mental Health. http://www.nimh.nih.gov/health/publications/schizophrenia/complete-publication.shtml.Accessed Sept. 29, 2010.
- Jibson MD. Schizophrenia: Diagnostic evaluation and treatment. http://www.uptodate.com/home/index.html. Accessed Sept. 29, 2010.
- Huey LY, et al. Families and schizophrenia: The view from advocacy. Psychiatric Clinics of North America. 2007;30:549.
- Rathod SR, et al. Cognitive behavioral therapy for schizophrenia. Psychiatric Clinics of North America. 2010;33:3.
- Staying well when you have a mental health condition. Mental Health America. http://www.nmha.org/go/mental-health-month/staying-well-when-you-have-a-mental-illness. Accessed Sept. 29, 2010.
- Daniels J. Catatonia: Clinical aspects and neurobiological correlates. The Journal of Neuropsychiatry and Clinical Neurosciences. 2009;21:371.
- Thirthalli J, et al. Does catatonic schizophrenia improve faster with electroconvulsive therapy than other subtypes of schizophrenia? The World Journal of Biological Psychiatry. 2009;10:772.
- Rosebush PI, et al. Catatonia and its treatment. Schizophrenia Bulletin. 2010;362:239.
- Hall-Flavin DK (expert opinion). Mayo Clinic, Rochester, Minn. Oct. 14, 2010.