Diagnosis at Mayo Clinic

By Mayo Clinic Staff

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To determine if you have calciphylaxis, your doctor will review your medical history, assess your symptoms and do a physical exam. Tests may include:

  • Deep skin biopsy. To diagnose calciphylaxis, your doctor may remove a small tissue sample from an area of affected skin for analysis.
  • Blood tests. Mayo Clinic labs will analyze a blood sample to measure a variety of substances in your blood — calcium, phosphorus, parathyroid hormone, aluminum, urea nitrogen, creatinine and albumin, among others — to help your doctor assess your kidney and liver function.
  • Imaging studies. X-rays may show branch-like calcium deposits in the blood vessels (vascular calcifications) that are common in calciphylaxis. However, vascular calcifications are also common in other advanced kidney diseases.

Read more about the blood urea nitrogen (BUN test), creatinine test and liver function tests.

June 18, 2015