Mayo Clinic conducts clinical trials to improve the diagnosis and treatment of bipolar disorder. Some areas of research include:
- Genetics and medication. Mayo is a leader in pharmacogenomics research, the study of how genetic factors can predict a person's response to a medication. One focus of Mayo Clinic research is connecting specific genetic profiles with responses to specific antidepressant drugs used to treat bipolar disorder.
- Treatment options for children and teens. Mayo Clinic psychiatrists are working with other specialists to determine the biological basis of bipolar disorder in children and to identify better, safer and more-effective treatments for children and teens.
- Drug treatment options. Mayo Clinic scientists conduct research to understand and identify the neuroanatomical and molecular changes in bipolar disorder. Their goal is to develop better and more-targeted drug treatment options based on variations in brain-imaging patterns, brain metabolism, and genetic and epigenetic makeup.
Mayo Clinic is serving as the primary site for the established Individualized Medicine Biobank for Bipolar Disorder. This large-scale biobank of bipolar type I and II disorders is intended to serve as a resource for the bipolar research community.
See a list of publications by Mayo Clinic doctors and researchers on bipolar disorder on PubMed, a service of the National Library of Medicine.