In Barrett's esophagus, tissue in the tube connecting your mouth and stomach (esophagus) is replaced by tissue similar to the intestinal lining.
Barrett's esophagus is most often diagnosed in people who have long-term gastroesophageal reflux disease (GERD) — a chronic regurgitation of acid from the stomach into the lower esophagus. Only a small percentage of people with GERD will develop Barrett's esophagus.
Barrett's esophagus is associated with an increased risk of developing esophageal cancer. Although the risk is small, it's important to have regular checkups for precancerous cells. If precancerous cells are discovered, they can be treated to prevent esophageal cancer.
Aug. 07, 2014
- Spechler SJ, et al. Epidemiology, clinical manifestations, and diagnosis of Barrett's esophagus. http://www.uptodate.com/home. Accessed Jan. 25, 2014.
- Feldman M, et al. Sleisenger & Fordtran's Gastrointestinal and Liver Disease: Pathophysiology, Diagnosis, Management. 9th ed. Philadelphia, Pa.: Saunders Elsevier; 2010. http://www.clinicalkey.com. Accessed Jan. 25, 2014.
- Spechler SJ, et al. Management of Barrett's esophagus. http://www.uptodate.com/home. Accessed Jan. 25, 2014.
- Ferri FF. Ferri's Clinical Advisor 2014: 5 Books in 1. Philadelphia, Pa.: Mosby Elsevier; 2014. https://www.clinicalkey.com. Accessed Jan. 25, 2014.
- AskMayoExpert. Who should be screened for Barrett esophagus? Rochester, Minn.: Mayo Foundation for Medical Education and Research; 2012.
- Estores D, et al. Barrett Esophagus: Epidemiology, pathogenesis, diagnosis, and management. Current Problems in Surgery. 2013;50:192.
- Nelsen EM, et al. Diagnosis and management of Barrett's esophagus. Surgical Clinics of North America. 2012;92:1135.
- Gorospe EC, et al. Risk stratification and surveillance in Barrett's esophagus. Nature Reviews Gastroenterology & Hepatology. In press. Accessed Jan. 25, 2014.
- Spechler SJ, et al. Pathogenesis of Barrett's esophagus and its malignant transformation. http://www.uptodate.com/home. Accessed Jan. 25, 2014.
- Qumseya BJ, et al. Advanced imaging technologies increase detection of dysplasia and neoplasia in patients with Barrett's esophagus: A meta-analysis and systematic review. Clinical Gastroenterology and Hepatology. 2013;11:1562.
- Bergman JJ, et al. Radiofrequency ablation for Barrett's esophagus. http://www.uptodate.com/home. Accessed Jan. 25, 2014.
- Tomizawa Y, et al. Assessment of the diagnostic performance and interobserver variability of endocytoscopy in Barrett's esophagus: A pilot ex-vivo study. World Journal of Gastroenterology. 2013;19:8652.
- Ek WE, et al. Germline genetic contributions to risk for esophageal adenocarcinoma, Barrett's esophagus, and gastroesophageal reflux. Journal of the National Cancer Institute. 2013;105:1711.
- Barrett's Esophagus. National Institute of Diabetes and Digestive and Kidney Diseases. http://digestive.niddk.nih.gov/ddiseases/pubs/barretts/index.aspx. Accessed Jan. 28, 2014.
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