Risk factorsBy Mayo Clinic Staff
Autism spectrum disorder affects children of all races and nationalities, but certain factors increase a child's risk. They include:
June 03, 2014
- Your child's sex. Boys are about four times more likely to develop ASD than girls are.
- Family history. Families who have one child with ASD have an increased risk of having another child with the disorder. It's also not uncommon for parents or relatives of a child with ASD to have minor problems with social or communication skills themselves or to engage in certain behaviors typical of ASD.
- Other disorders. Children with certain medical conditions have a higher than normal risk of ASD or ASD-like symptoms. Examples of these conditions include fragile X syndrome, an inherited disorder that causes intellectual problems; tuberous sclerosis, a condition in which benign tumors develop in the brain; the neurological disorder Tourette syndrome; and Rett syndrome, a genetic condition occurring almost exclusively in girls, which causes slowing of head growth, intellectual disability and loss of purposeful hand use.
- Extremely preterm babies. Babies born before 26 weeks of pregnancy may have a greater risk of ASD.
- Parents' ages. There may also be a connection between children born to older parents and ASD, but more research is necessary to establish this link.
- Autism spectrum disorder (ASD). Eunice Kennedy Shriver National Institute of Child Health & Human Development. http://www.nichd.nih.gov/health/topics/autism/Pages/default.aspx. Accessed Feb. 24, 2014.
- Volkmar F, et al. Practice parameter for the assessment and treatment of children and adolescents with autism spectrum disorder. Journal of the American Academy of Child and Adolescent Psychiatry. 2014;53:237.
- LaBlanc LA, et al. Behavioral interventions for children with autism spectrum disorders. Pediatric Clinics of North America. 2012;59:147.
- Autism spectrum disorder. In: Diagnostic and Statistical Manual of Mental Disorders DSM-5. 5th ed. Arlington, Va.: American Psychiatric Association; 2013. http://www.psychiatryonline.org. Accessed Feb. 24, 2014.
- Weissman L, et al. Autism spectrum disorder in children and adolescents: Complementary and alternative therapies. http://www.uptodate.com/home. Accessed Feb. 24, 2014.
- Learn the signs — Act early: Concerned. Centers for Disease Control and Prevention. http://www.cdc.gov/ncbddd/actearly/concerned.html. Accessed Feb. 24, 2014.
- Autism spectrum disorder. American Psychiatric Association. http://www.psychiatry.org/dsm5. Accessed Feb. 24, 2014.
- A parent's guide to autism spectrum disorder. National Institute of Mental Health. http://www.nimh.nih.gov/health/publications/a-parents-guide-to-autism-spectrum-disorder/what-are-the-symptoms-of-asd.shtml. Accessed Feb. 24, 2014.
- Augustyn M. Terminology, epidemiology, and pathogenesis of autism spectrum disorder. http://www.uptodate.com/home. Accessed Feb. 24, 2014.
- Bridgemohan C. Surveillance and screening for autism spectrum disorder in primary care. http://www.uptodate.com/home. Accessed Feb. 24, 2014.
- Cheuk DKL, et al. Acupuncture for autism spectrum disorders (ASD). Cochrane Database of Systematic Reviews. http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD007992.pub2/abstract. Accessed March 3, 2014.
- American Academy of Pediatrics policy statement: Sensory integration therapies for children with developmental and behavioral disorders. Pediatrics. 2012;129:1186.
- Autism spectrum disorders (ASDs): Do vaccines cause autism spectrum disorders (ASDs)? Centers for Disease Control and Prevention. http://www.cdc.gov/ncbddd/autism/topics.html. Accessed Feb. 24, 2014.
- Autism fact sheet. National Institute of Neurological Disorders and Stroke. http://www.ninds.nih.gov/disorders/autism/detail_autism.htm. Accessed Feb. 24, 2014.
- Highlights of changes from DSM-IV-TR to DSM-5. American Psychiatric Association. http://www.psychiatry.org/dsm5. Accessed Feb. 24, 2014.
- Chelation: Therapy or "therapy"? National Capital Poison Center. http://www.poison.org/current/chelationtherapy.htm. Accessed Feb. 24, 2014.
- Patterson MC (expert opinion). Mayo Clinic, Rochester, Minn. March 24, 2014.
- Tervo RC (expert opinion). Mayo Clinic, Rochester, Minn. March 28, 2014.