Alternative medicine

By Mayo Clinic Staff

Make sure you understand the risks as well as possible benefits if you pursue alternative or complementary therapy. Don't replace conventional medical treatment or psychotherapy with alternative medicine. When it comes to depression, alternative treatments aren't a substitute for professional care.

Herbal remedies and supplements

Examples of herbal remedies and supplements that are sometimes used for depression include:

  • St. John's wort. This herb is not approved by the Food and Drug Administration to treat depression in the United States, but it's a popular depression treatment in Europe. It may be helpful if you have mild or moderate depression, but St. John's wort should be used with caution. It can interfere with a number of medications, including antidepressants, HIV/AIDS medications, drugs to prevent organ rejection after an organ transplant, birth control pills, blood-thinning medications and chemotherapy drugs.
  • SAMe. Pronounced "sam-EE," this dietary supplement is a synthetic form of a chemical that occurs naturally in the body. The name is short for S-adenosylmethionine (uh-den-o-sul-muh-THIE-o-neen). Like St. John's wort, SAMe isn't approved by the FDA to treat depression in the United States, but it's used in Europe as a prescription drug to treat depression. SAMe may be helpful, but more research is needed. In higher doses, SAMe can cause nausea and constipation.
  • Omega-3 fatty acids. These healthy fats are found in cold-water fish, flaxseed, flax oil, walnuts and some other foods. Omega-3 supplements are being studied as a possible treatment for depression. While considered generally safe, the supplement can have a fishy taste, and in high doses, it may interact with other medications. More research is needed to determine if eating foods with omega-3 fatty acids can help relieve depression.

Because some herbal and dietary supplements can interfere with prescription medications or cause dangerous interactions, talk with your health care provider before taking any supplements.

Mind-body connections

Complementary and alternative medicine practitioners believe the mind and body must be in harmony for you to stay healthy. Examples of mind-body techniques that may be helpful for depression include:

  • Acupuncture
  • Yoga or tai chi
  • Meditation
  • Guided imagery
  • Massage therapy
  • Relaxation techniques
  • Music or art therapy
  • Spirituality

Relying solely on these therapies is generally not enough to treat depression. They may be helpful when used in addition to medication and psychotherapy.

Sep. 20, 2012