Allergies and asthma: A Mayo Clinic specialist explains the connection, and what you can do to prevent attacks and manage symptoms.
By Mayo Clinic Staff
You may wonder what allergies and asthma have in common besides making you miserable. A lot, as it turns out. Allergies and asthma often occur together.
The same substances that trigger your hay fever symptoms, such as pollen, dust mites and pet dander, may also cause asthma signs and symptoms. In some people, skin or food allergies can cause asthma symptoms. This is called allergic asthma or allergy-induced asthma.
James T C Li, M.D., Ph.D., a Mayo Clinic allergy specialist, answers questions about the link between allergies and asthma.
An allergic response occurs when immune system proteins (antibodies) mistakenly identify a harmless substance, such as tree pollen, as an invader. In an attempt to protect your body from the substance, antibodies bind to the allergen.
The chemicals released by your immune system lead to allergy signs and symptoms, such as nasal congestion, runny nose, itchy eyes or skin reactions. For some people, this same reaction also affects the lungs and airways, leading to asthma symptoms.
Most treatments are designed to treat either asthma or allergies. But a few treatments help with both conditions. Some examples:
Leukotriene modifier. Montelukast (Singulair) can ease both allergy and asthma symptoms. Called a leukotriene modifier, this daily pill helps control immune system chemicals released during an allergic reaction.
In rare cases, montelukast has been linked to psychological reactions, including suicidal thinking. Seek medical advice right away for any unusual psychological reaction to one of these medications.
Allergy shots (immunotherapy). Allergy shots can help treat asthma by gradually reducing your immune-system response to certain allergy triggers. Immunotherapy involves getting regular injections of a tiny amount of the allergens that trigger your symptoms.
Your immune system builds up a tolerance to the allergens over time, and your allergic reactions diminish. In turn, asthma symptoms decrease as well. This treatment generally requires regular injections over a period of three to five years.
Anti-immunoglobulin E (IgE) therapy. When you have an allergy, your immune system mistakenly identifies a specific substance as something harmful and releases antibodies, known as IgE, against the culprit allergen.
The next time you encounter that allergen, the IgE antibodies sense it and signal your immune system to release a chemical called histamine, as well as other chemicals, into your bloodstream. The medication omalizumab (Xolair) interferes with IgE in the body and helps prevent the allergic reaction that triggers asthma symptoms.
You may need other medications to treat allergies or asthma, especially if your symptoms become severe at times. However, recognizing and avoiding the substances that trigger your symptoms is the most important step you can take.
A family history of allergies is a major risk factor for allergic asthma. Having hay fever or other allergies yourself also increases your risk of getting asthma.
Though allergic asthma is very common, there are other types of asthma with different kinds of triggers. For some people, asthma can be triggered by exercise, infections, cold air, gastroesophageal reflux disease or stress. Many people have more than one kind of asthma trigger.
Know the things that trigger your allergy and asthma symptoms and learn how to limit your exposure to them. Work with your doctor to find the best treatment to manage your symptoms, and check in with your doctor on a regular basis.
Because allergy and asthma symptoms can change over time, you may need to adjust your treatment accordingly. Learn the signs that your asthma may be flaring up — and know what to do when it does.
Feb. 13, 2016
- Adkinson NF, et al. Asthma pathogenesis. In: Middleton's Allergy: Principles and Practice. 8th ed. Philadelphia, Pa.: Saunders Elsevier; 2014. http://www.clinicalkey.com. Accessed Dec. 8, 2015.
- Asthma information. American College of Allergy, Asthma and Immunology. http://acaai.org/asthma/about. Accessed Dec. 8, 2015.
- Baldacci S, et al. Allergy and asthma: Effects of the exposure to particulate matter and biological allergens. Respiratory Medicine. 2015;109:1089.
- Asthma symptoms. American College of Allergy, Asthma and Immunology. http://acaai.org/asthma/symptoms. Accessed Dec. 8, 2015.
- National Asthma Education and Prevention Program expert panel report 3: Guidelines for the diagnosis and management of asthma. National Institutes of Health. http://www.nhlbi.nih.gov/health-pro/guidelines/current/asthma-guidelines/full-report. Accessed Dec. 9, 2015.
- Global strategy for asthma management and prevention (2015 update). Global Initiative for Asthma. http://www.ginasthma.org/documents/4. Accessed Dec. 9, 2015.
- Updated information on leukotriene inhibitors: Montelukast (marketed as Singulair), zafirlukast (marketed as Accolate), and zileuton (marketed as Zyflo and Zyflo CR). U.S. Food and Drug Administration. http://www.fda.gov/Drugs/DrugSafety/PostmarketDrugSafetyInformationforPatientsandProviders/DrugSafetyInformationforHeathcareProfessionals/ucm165489.htm. Accessed Dec. 9, 2015.