DefinitionBy Mayo Clinic Staff
Aspergillosis is an infection caused by a type of mold. The illnesses resulting from aspergillosis infection usually affect the respiratory system, but their signs and severity vary greatly. The mold that triggers the illnesses, aspergillus, is everywhere, indoors and outdoors. Most strains of this mold are harmless, but a few can cause serious illnesses when people with weakened immune systems, underlying lung disease or asthma inhale their spores.
In some people, the spores trigger an allergic reaction. Other people develop mild to serious lung infections. The most serious form of aspergillosis — invasive aspergillosis — occurs when the infection spreads to blood vessels and beyond.
Depending on the type of aspergillosis, treatment may involve observation, antifungal medications or, in rare cases, surgery.
Aug. 05, 2014
- Aspergillosis. Centers for Disease Control and Prevention. http://www.cdc.gov/fungal/aspergillosis/. Accessed Nov. 12, 2013.
- Goldman L, et al. Cecil Medicine. 24th ed. Philadelphia, Pa.: Saunders Elsevier; 2012. http://www.clinicalkey.com. Accessed Nov. 12, 2013.
- Ferri FF. Ferri's Clinical Advisor 2013: 5 Books in 1. Philadelphia, Pa.: Mosby Elsevier; 2013. https://www.clinicalkey.com. Accessed Nov. 12, 2013.
- Marr KA. Treatment and prevention of invasive aspergillosis. http://www.uptodate.com/home. Accessed Nov. 11, 2013.
- Treatment of aspergillosis. Arlington, Va.: Infectious Diseases Society of America. Clinical Infectious Diseases. 2008;46:327.
- Marr KA. Epidemiology and clinical manifestations of of invasive aspergillosis. http://www.uptodate.com/home. Accessed Nov. 11, 2013.
- Denning DW, et al. Clinical manifestations and diagnosis of chronic pulmonary aspergillosis. http://www.uptodate.com/home. Accessed Dec. 6, 2013.