Atherosclerosis develops gradually. Mild atherosclerosis usually doesn't have any symptoms.
You usually won't have atherosclerosis symptoms until an artery is so narrowed or clogged that it can't supply adequate blood to your organs and tissues. Sometimes a blood clot completely blocks blood flow, or even breaks apart and can trigger a heart attack or stroke.
Symptoms of moderate to severe atherosclerosis depend on which arteries are affected. For example:
- If you have atherosclerosis in your heart arteries, you may have symptoms, such as chest pain or pressure (angina).
- If you have atherosclerosis in the arteries leading to your brain, you may have signs and symptoms such as sudden numbness or weakness in your arms or legs, difficulty speaking or slurred speech, or drooping muscles in your face. These signal a transient ischemic attack (TIA), which, if left untreated, may progress to a stroke.
- If you have atherosclerosis in the arteries in your arms and legs, you may have symptoms of peripheral artery disease, such as leg pain when walking (intermittent claudication).
- If you have atherosclerosis in the arteries leading to your kidneys, you develop high blood pressure or kidney failure.
- If you have atherosclerosis in the arteries leading to your genitals, you may have difficulties having sex. Sometimes, atherosclerosis can cause erectile dysfunction in men. In women, high blood pressure can reduce blood flow to the vagina, making sex less pleasurable.
When to see a doctor
If you think you have atherosclerosis, talk to your doctor. Also pay attention to early symptoms of inadequate blood flow, such as chest pain (angina), leg pain or numbness. Early diagnosis and treatment can stop atherosclerosis from worsening and prevent a heart attack, stroke or another medical emergency.
May. 30, 2014
- What is atherosclerosis? National Heart, Lung, and Blood Institute. http://www.nhlbi.nih.gov/health/dci/Diseases/Atherosclerosis/Atherosclerosis_All.html. Accessed Oct. 2, 2013.
- Atherosclerosis. American Heart Association. http://www.heart.org/HEARTORG/Conditions/Cholesterol/WhyCholesterolMatters/Atherosclerosis_UCM_305564_Article.jsp. Accessed Oct. 2, 2013.
- Zhao X. Pathogenesis of atherosclerosis. http://www.uptodate.com/home. Accessed Oct. 2, 2013.
- Kalanuria AA, et al. The prevention and regression of atherosclerosis plaques: Emerging treatments. Vascular Health and Risk Management. 2012;8:549.
- Smith SC, et al. American Heart Association/American College of Cardiology Foundation Secondary prevention and risk reduction therapy for patients with coronary and other atherosclerotic vascular disease: 2011 update. Circulation. 2011;124:2458.
- The seventh report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure. National Heart, Lung, and Blood Institute. http://www.nhlbi.nih.gov/guidelines/hypertension/jnc7full.htm. Accessed Oct. 3, 2013.
- Natural product effectiveness checker: High cholesterol. Natural Medicines Comprehensive Database. http://www.naturaldatabase.com. Accessed Oct. 3, 2013.
- Natural product effectiveness checker: Atherosclerosis. Natural Medicines Comprehensive Database. http://www.naturaldatabase.com. Accessed Oct. 3, 2013.
- Natural product effectiveness checker: Hypertension. Natural Medicines Comprehensive Database. http://www.naturaldatabase.com. Accessed Oct. 3, 2013.
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