Several herbal remedies have been studied as a treatment for anxiety, such as kava, valerian and passionflower, but more research is needed to understand the risks and benefits. Here's what researchers know — and don't know:
- Kava. Kava appeared to be a promising treatment for anxiety, but reports of serious liver damage — even with short-term use — caused several European countries and Canada to pull it off the market. The Food and Drug Administration has issued warnings but not banned sales in the United States. Avoid using kava until more rigorous safety studies are done, especially if you have liver problems or take medications that affect your liver.
- Valerian. In some studies, people who used valerian reported less anxiety and stress, but in other studies, people reported no benefit. Discuss valerian with your doctor before trying it. Some people who have used high doses or used it long term may have increased their risk of liver damage, although it's not clear if valerian caused the damage. When it's time to stop using valerian, it must be tapered down to prevent withdrawal symptoms.
- Passionflower. A few small clinical trials suggest that passionflower might help with anxiety. In many commercial products, passionflower is combined with other herbs, making it difficult to distinguish the unique qualities of each herb. Passionflower is generally considered safe when taken as directed, but some studies found it can cause drowsiness, dizziness and confusion.
- Theanine. This amino acid is found in green tea and may be found in some supplements. Preliminary evidence shows that theanine may make some people feel calmer, but there is no evidence that it helps treat anxiety.
Before taking herbal remedies or supplements, talk to your doctor to make sure they're safe for you and won't interact with any medications you take.
Aug. 15, 2014
- Anxiety disorders. In: Diagnostic and Statistical Manual of Mental Disorders DSM-5. 5th ed. Arlington, Va.: American Psychiatric Association; 2013. http://www.psychiatryonline.org. Accessed Oct. 11, 2013.
- Highlights of changes from DSM-IV-TR to DSM-5. American Psychiatric Association. http://www.dsm5.org/Documents/changes%20from%20dsm-iv-tr%20to%20dsm-5.pdf. Accessed Oct. 8, 2013.
- Anxiety disorders. National Institute of Mental Health. http://www.nimh.nih.gov/health/topics/anxiety-disorders/index.shtml. Accessed Oct. 11, 2013.
- Facts for families: The anxious child. American Academy of Child and Adolescent Psychiatry. http://www.aacap.org/AACAP/Families_and_Youth/Facts_for_Families/Facts_for_Families_Pages/The_Anxious_Child_47.aspx. Accessed Oct. 11, 2013.
- U.S. News best hospitals 2012-2013. U.S. News & World Report. http://health.usnews.com/best-hospitals/rankings. Accessed Dec. 10, 2013.
- Bystritsky A. Pharmacotherapy for generalized anxiety disorder. http://www.uptodate.com/home. Accessed Oct. 11, 2013.
- Mayo-Wilson E, et al. Media-delivered cognitive behavioural therapy and behavioural therapy (self-help) for anxiety disorders in adults. Cochrane Database Systematic Reviews. http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD005330.pub3/abstract. Accessed Oct. 11, 2013.
- Ravindran AV, et al. Complementary and alternative therapies as add-on to pharmacotherapy for mood and anxiety disorders: A systematic review. Journal of Affective Disorders. 2013;15:707.
- Rakel D. Integrative Medicine. 3rd ed. Philadelphia, Pa.: Saunders Elsevier; 2012. http://www.clinicalkey.com. Accessed Oct. 11, 2013.
- Natural medicines in the clinical management of anxiety. Natural Medicines Comprehensive Database. http://www.naturaldatabase.com. Accessed Oct. 11, 2013.
- Support & programs. National Alliance on Mental Illness. http://www.nami.org/Template.cfm?section=Find_Support. Accessed Oct. 11, 2013.
- Getting support. Anxiety and Depression Association of America. http://www.adaa.org/finding-help/getting-support. Accessed Oct. 11, 2013.
- Sarris J, et al. Plant-based medicines for anxiety disorders, Part 2: A review of clinical studies with supporting preclinical evidence. CNS Drugs. 2013;27:301.
- Kava. Natural Medicines Comprehensive Database. http://www.naturaldatabase.com. Accessed Oct. 17, 2013.
- Valerian. Natural Medicines Comprehensive Database. http://www.naturaldatabase.com. Accessed Oct. 17, 2013.
- Passionflower. Natural Medicines Comprehensive Database. http://www.naturaldatabase.com. Accessed Oct. 17, 2013.
- FDA drug safety communication: Revised recommendations for Celexa (citalopram hydrobromide) related to potential risk of abnormal heart rhythms with high doses. U.S. Food and Drug Administration. http://www.fda.gov/drugs/drugsafety/ucm297391.htm. Accessed Oct. 28, 2013.
- Bauer BA (expert opinion). Mayo Clinic, Rochester, Minn. Oct. 28, 2013.
- Whiteside SP (expert opinion). Mayo Clinic, Rochester, Minn. Nov. 27, 2013.
- Theanine. Natural Medicines Comprehensive Database. http://www.naturaldatabase.com. Accessed Dec. 3, 2013.
- Sawchuk CN (expert opinion). Mayo Clinic, Rochester, Minn. Dec. 5, 2013.
- Hall-Flavin DK (expert opinion). Mayo Clinic, Rochester, Minn. Dec. 5, 2013.
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