Certain factors make anhidrosis more likely, including:

  • Age. As you grow older, your ability to sweat normally may diminish, usually because your body has more trouble regulating its temperature.
  • Certain health problems. Any medical condition that damages your autonomic nerves makes sweat gland problems more likely. Diabetes is a common condition that can cause nerve damage, but a number of other diseases can injure both nerves and sweat glands, often in a specific area, such as your legs or face.
  • Skin disorders. Many diseases that irritate or inflame the skin also affect the sweat glands. Anhidrosis can occur with a number of skin disorders, including psoriasis; exfoliative dermatitis, which is marked by severe skin scaling; heat rash; scleroderma, which causes hard, tight skin; and ichthyosis — extremely dry, scaly skin.
  • Genetic abnormalities. Mutations in certain genes can lead to disorders that affect the sweat glands.
Feb. 15, 2012