Treatment

There's no cure for Angelman syndrome. Research is focusing on targeting specific genes for treatment. Current treatment focuses on managing the medical and developmental issues.

A team of health care professionals will likely work with you to manage your child's condition. Depending on your child's signs and symptoms, treatment for Angelman syndrome may involve:

  • Anti-seizure medication to control seizures
  • Physical therapy to help with walking and movement problems
  • Communication therapy, which may include sign language and picture communication
  • Behavior therapy to help overcome hyperactivity and a short attention span and to aid in development
Feb. 07, 2017
References
  1. NINDS Angelman syndrome information page. National Institute of Neurological Disorders and Stroke. http://www.ninds.nih.gov/disorders/angelman/angelman.htm. Accessed Nov. 7, 2016.
  2. National Library of Medicine. Angelman syndrome. Genetics Home Reference. http://ghr.nlm.nih.gov/condition/angelman-syndrome. Accessed Nov. 7, 2016.
  3. Angelman syndrome diagnostic criteria. Angelman Syndrome Foundation. http://www.angelman.org/understanding-as/medical-info/diagnostic-criteria/. Accessed Nov. 7, 2016.
  4. Pagon RA, et al., eds. Angelman syndrome. In: GeneReviews. Seattle, Wash.: University of Seattle, Washington; 1993-2016. http://www.ncbi.nlm.nih.gov/books/NBK1116. Accessed Nov. 7, 2016.
  5. Bailus BJ, et al. The prospect of molecular therapy for Angelman syndrome and other monogenic neurologic disorders. BMC Neuroscience. 2014;15:76.
  6. Angelman syndrome diagnostic testing. Angelman Syndrome Foundation. https://www.angelman.org/what-is-as/medical-information/diagnostic-testing/. Accessed Nov. 13, 2016.
  7. Buiting K, et al. Angelman syndrome — Insights into a rare neurogenetic disorder. Nature. 2016;12:584.
  8. Patterson MC (expert opinion). Mayo Clinic, Rochester, Minn. Nov. 22, 2016.