Complications associated with Angelman syndrome include:

  • Feeding difficulties. An inability to coordinate sucking and swallowing may cause feeding problems during the infant's early months. Your pediatrician may recommend a high-calorie formula to help your baby gain weight.
  • Hyperactivity. Moving quickly from one activity to another, short attention span, and keeping hands or a toy in their mouths may characterize children with Angelman syndrome. Hyperactivity often decreases with age, and medication usually isn't necessary.
  • Sleep disorders. People with Angelman syndrome often have abnormal sleep-wake patterns and need less sleep than normal. In some cases, sleep difficulties may improve with age. Medication and behavior therapy may help control sleep disorders.
  • Curving of the spine (scoliosis). Some people with Angelman syndrome develop an abnormal side-to-side spinal curvature over time.
  • Obesity. Older children with Angelman syndrome tend to have large appetites, which may lead to obesity.
Dec. 05, 2014

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