Complications associated with Angelman syndrome include:
Dec. 05, 2014
- Feeding difficulties. An inability to coordinate sucking and swallowing may cause feeding problems during the infant's early months. Your pediatrician may recommend a high-calorie formula to help your baby gain weight.
- Hyperactivity. Moving quickly from one activity to another, short attention span, and keeping hands or a toy in their mouths may characterize children with Angelman syndrome. Hyperactivity often decreases with age, and medication usually isn't necessary.
- Sleep disorders. People with Angelman syndrome often have abnormal sleep-wake patterns and need less sleep than normal. In some cases, sleep difficulties may improve with age. Medication and behavior therapy may help control sleep disorders.
- Curving of the spine (scoliosis). Some people with Angelman syndrome develop an abnormal side-to-side spinal curvature over time.
- Obesity. Older children with Angelman syndrome tend to have large appetites, which may lead to obesity.
- NINDS Angelman syndrome information page. National Institute of Neurological Disorders and Stroke. http://www.ninds.nih.gov/disorders/angelman/angelman.htm. Accessed Oct. 6, 2014.
- Angelman syndrome. Genetics Home Reference. http://ghr.nlm.nih.gov/condition/angelman-syndrome. Accessed Oct. 6, 2014.
- Angelman syndrome diagnostic criteria. Angelman Syndrome Foundation. http://www.angelman.org/understanding-as/medical-info/diagnostic-criteria/. Accessed Oct. 6, 2014.
- Angelman syndrome diagnostic testing. Angelman Syndrome Foundation. http://www.angelman.org/understanding-as/medical-info/diagnostic-testing/. Accessed Oct. 6, 2014.
- Bailus BJ, et al. The prospect of molecular therapy for Angelman syndrome and other monogenic neurologic disorders. BMC Neuroscience. 2014;15:76.