The main types of amyloidosis include primary amyloidosis, secondary amyloidosis and hereditary amyloidosis. An accurate diagnosis is essential so that you receive the appropriate treatment. Mayo Clinic is one of the few centers in the United States that offers leading-edge diagnostic technologies and top-quality expertise to determine the specific type of amyloid protein that is building up in your body.
Your doctor may recommend blood or urine tests to detect an abnormal protein, which could indicate amyloidosis. However, the only definitive test for amyloidosis is a tissue biopsy. Mayo Clinic offers specialized analysis of the amyloid deposits — such as immunostaining or chemical analysis with a test called mass spectrometry — to confirm amyloidosis and to identify the type that you have.
Aug. 06, 2011
- Gorevic PD. An overview of amyloidosis. http://www.uptodate.com/home/index.html. Accessed June 25, 2011.
- Amyloidosis. The Merck Manuals: The Merck Manual for Healthcare Professionals. http://www.merckmanuals.com/professional/sec12/ch160/ch160a.html. Accessed June 25, 2011.
- Naqvi BH, et al. Amyloidosis. In: Ferri FF. Ferri's Clinical Advisor 2011: Instant Diagnosis and Treatment. Philadelphia, Pa.: Mosby Elsevier; 2011. http://www.mdconsult.com/books/about.do?eid=4u1.0-B978-0-323-05610-6..C2009-0-38600-6--TOP&isbn=978-0-323-05610-6&about=true&uniqId=230100505-53. Accessed June 25, 2011.
- Seldin DC, et al. Amyloidosis. In: Fauci AS, et al. Harrison's Online. 17th ed. New York, N.Y.: The McGraw-Hill Companies; 2008. http://www.accessmedicine.com/content.aspx?aID=2863105. Accessed June 25, 2011.
- Rajkumar SV. Prognosis and treatment of immunoglobulin light chain (AL) amyloidosis and light and heavy chain deposition diseases. http://www.uptodate.com/home/index.html. Accessed June 25, 2011.
- Gertz MA (expert opinion). Mayo Clinic, Rochester, Minn. June 26, 2011.
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