Treatments and drugs

By Mayo Clinic Staff

There's no cure for amyloidosis. But treatment can help manage signs and symptoms and limit further production of amyloid protein. Specific treatments depend on the type of amyloidosis.

For AL amyloidosis, treatment options include:

  • Chemotherapy, to stop the growth of abnormal cells that produce amyloid.
  • Peripheral blood stem cell transplant, in which your own stem cells are collected from your blood and stored for a short time while you have high-dose chemotherapy. The stem cells are then returned to your body via a vein. This treatment is most appropriate for people whose disease isn't advanced and whose heart isn't greatly affected.

Treatment for other types of amyloidosis

  • AA amyloidosis. The underlying condition is treated with medication — for example, an anti-inflammatory medication to treat rheumatoid arthritis.
  • Hereditary amyloidosis. Liver transplantation may be an option because the protein that causes this form of amyloidosis is made in the liver.
  • Dialysis-related amyloidosis. Options include changing your mode of dialysis or having a kidney transplant.

Medications

To manage ongoing signs and symptoms of amyloidosis, your doctor also may recommend:

  • Pain medication
  • Fluid retention medication (diuretic) and a low-salt diet
  • Blood-thinning medication
  • Medication to control your heart rate
Jul. 29, 2014

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