Family history may play a role in the development of ambiguous genitalia, because many disorders of sex development result from genetic abnormalities that can be inherited. Possible risk factors for ambiguous genitalia include a family history of:

  • Unexplained deaths in early infancy
  • Infertility, absent menstrual periods or excess facial hair in females
  • Genital abnormalities
  • Abnormal physical development during puberty
  • Congenital adrenal hyperplasia

If your family has a history of these risk factors, consider seeking medical advice before trying to conceive. You may also benefit from genetic counseling.

Mar. 16, 2012