Overview

Achalasia is a rare disorder that makes it difficult for food and liquid to pass into your stomach. Achalasia occurs when nerves in the tube connecting your mouth and stomach (esophagus) become damaged. As a result, the esophagus loses the ability to squeeze food down, and the muscular valve between the esophagus and stomach (lower esophageal sphincter) doesn't fully relax — making it difficult for food to pass into your stomach.

There's no cure for achalasia. But symptoms can usually be managed with minimally invasive therapy or surgery.

Achalasia care at Mayo Clinic

July 11, 2017
References
  1. Spechler SJ. Achalasia: Pathogenesis, clinical manifestations, and diagnosis. http://www.uptodate.com/home. Accessed Feb. 3, 2017.
  2. Feldman M, et al. Esophageal neuromuscular function and motility disorders. In: Sleisenger and Fordtran's Gastrointestinal and Liver Disease: Pathophysiology, Diagnosis, Management. 10th ed. Philadelphia, Pa.: Saunders Elsevier; 2016. http://www.clinicalkey.com. Accessed Jan. 17, 2017.
  3. Sawas T, et al. The course of achalasia one to four decades after initial treatment. Alimentary Pharmacology and Therapeutics. 2017;45:553.
  4. Spechler SJ. Overview of the treatment of achalasia. http://www.uptodate.com/home. Accessed Feb. 3, 2017.
  5. Krill JT, et al. Clinical management of achalasia: Current state of the art. Clinical and Experimental Gastroenterology. 2016;9:71.
  6. Bechara R, et al. POEM, the prototypical 'new NOTES' procedure and first successful NOTES procedure. Gastrointestinal Endoscopy Clinics of North America. 2016;26:237.
  7. Patti MG, et al. POEM vs laparoscopic Heller myotomy and fundoplication: Which is now the gold standard for treatment of achalasia? Journal of Gastrointestinal Surgery. 2017;21:207.
  8. Brown AY. Allscripts EPSi. Mayo Clinic, Rochester, Minn. Jan. 24, 2017.