Diabetes

Clinical Trials

Below is a list of Diabetes clinical trials from the clinical trials database at Mayo Clinic.

This list includes only trials about which Mayo researchers choose to publish information. Mayo Clinic may be conducting other trials which are not in this database. Mayo's clinical trials include experimental treatments, often unavailable elsewhere, which frequently lead to improved patient care for people worldwide. Patients should ask their doctor at Mayo about clinical trials appropriate for their situation.

An Evaluation of the Metabolic Effects of Exenatide, Rosiglitazone, and Exenatide plus Rosiglitazone in Subjects with Type 2 Diabetes Treated with Metformin
This study is being done to compare the effects of two drugs for the treatment of type 2 diabetes. This study will evaluate the effects of adding exenatide, rosiglitazone, or both to your current oral antidibetic medication (metformin). The study will evaluate the effects of these medications on beta cell function, insulin sensitivity, blood glucose control and body weight.
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Effect of Insulin Sensitizers on Lipid Metabolism in Obese, Dyslipidemic Subjects with Type 2 Diabetes
This research study is being done to learn about the effects of two medications for type 2 diabetes, pioglitazone and metformin, on triglyceride metabolism after a meal. This is important because elevated triglyceride levels after meals are associated with increased risk of heart attack.
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Pirfenidone: A Novel Anti-Scarring Therapy for Advanced Diabetic Nephropathy
The purpose of this research study is to find out whether the investigational drug, pirfenidone, can slow or reverse the development of progressive kidney disease in diabetic patients. The study is supported by the National Institutes of Health (NIH).
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The Effect of an Investigational Drug on Blood Flow and Control of Blood Sugar in Subjects with Type 2 Diabetes Mellitus
Effect of an investigational drug, liraglutide vs placebo or a well known FDA approved anti-diabetic drug, glimepiride, in subjects with type 2 diabetes to see if liraglutide will improve blood flow and blood sugar control. Individuals on diet or metformin alone may be eligible.
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The Effect of Insulin Sensitizers on Mitochondrial ATP Production and Mitochondrial Protein Synthesis on Insulin Resistant Type 2 Diabetic and Obese People
This study is being done to determine the effects of Pioglitazone (Actos) and Metformin on muscle metabolism.
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Use of Pyridostigmine for Constipation in Diabetics
The purpose of this research study is to learn if pyridostigmine, a drug, affects the speed at which food travels through the stomach, intestines and colon, and if pyridostigmine improves constipation symptoms in patients with diabetes. Pyridostigmine has been approved by the Food and Drug Administration (FDA) for routine clinical use, however, its use as proposed in this study is considered investigational.
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