Depression

Research

Mayo Clinic has made a number of important contributions to research on depression, especially depression as it relates to other medical problems and other psychiatric disorders or addictions. Mayo researchers have made contributions to new developments in electroconvulsive therapy. Mayo has also developed a new blood test, the cytochrome P450 test, that helps pinpoint genetic factors that play a role in a patient's response to most antidepressant medications. Mayo is constantly conducting clinical trials to improve the diagnosis and treatment of depression.

Publications

Townsend CO, Sletten CD, Bruce BK, Rome JD, Luedtke CA, Hodgson JE. Physical and emotional functioning of adult patients with chronic abdominal pain: Comparison with patients with chronic back pain. Journal of Pain. 2005 Feb;6(2):75-83. [Abstract]

Rasmussen KG, Snyder KA, Knapp RG, Mueller M, Yim E, Husain MM, Rummans TA, Sampson SM, O'connor MK, Bernstein HJ, Kellner CH; the rest of the CORE Group. Relationship between somatization and remission with ECT. Psychiatry Research. 2004 Dec 30;129(3):293-5. [Abstract]

Vickers KS, Patten CA, Bronars C, Lane K, Stevens SR, Croghan IT, Schroeder DR, Clark MM. Binge drinking in female college students: the association of physical activity, weight concern, and depressive symptoms. Journal of American College Health. 2004 Nov-Dec;53(3):133-40. [Abstract]

Vander Weg MW, Ward KD, Scarinci IC, Read MC, Evans CB. Smoking-related correlates of depressive symptoms in low-income pregnant women. American Journal of Health Behavior. 2004 Nov-Dec;28(6):510-21. [Abstract]

Tucker S, Brust S, Pierce P, Fristedt C, Pankratz VS. Depression coping self-efficacy as a predictor of relapse 1 and 2 years following psychiatric hospital-based treatment. Research and Theory for Nursing Practice. 2004 Summer-Fall;18(2-3):261-75. [Abstract]

Sim L, Zeman J. Emotion awareness and identification skills in adolescent girls with bulimia nervosa. Journal of Clinical Child and Adolescent Psychology. 2004 Dec;33(4):760-71. [Abstract]

Abramowitz JS. Treatment of obsessive-compulsive disorder in patients who have comorbid major depression. Journal of Clinical Psychology. 2004 Nov;60(11):1133-41. [Abstract]

Cox LS, Patten CA, Niaura RS, Decker PA, Rigotti N, Sachs DP, Buist AS, Hurt RD. Efficacy of bupropion for relapse prevention in smokers with and without a past history of major depression. Journal of General Internal Medicine. 2004 Aug;19(8):828-34. [Abstract]

Grambsch P, Young EA, Meller WH. Pulsatile luteinizing hormone disruption in depression. Psychoneuroendocrinology. 2004 Aug;29(7):825-9. [Abstract]

Karpyak VM, Rasmussen KG, Hammill SC, Mrazek DA. Changes in heart rate variability in response to treatment with electroconvulsive therapy. Journal of ECT. 2004 Jun;20(2):81-8. [Abstract]

Robertson M, Rushton PJ, Bartrum D, Ray R. Group-based interpersonal psychotherapy for posttraumatic stress disorder: theoretical and clinical aspects. International Journal of Group Psychotherapy. 2004 Apr;54(2):145-75. [Abstract]

Good MS, Dolenc TJ, Rasmussen KG. Electroconvulsive therapy in a patient with glaucoma. Journal of ECT. 2004 Mar;20(1):48-9. [Abstract]

Rasmussen KG, Karpyak VM, Hammill SC. Lack of effect of ECT on Holter monitor recordings before and after treatment. Journal of ECT. 2004 Mar;20(1):45-7. [Abstract]

Lapid MI, Rummans TA, Pankratz VS, Appelbaum PS. Decisional capacity of depressed elderly to consent to electroconvulsive therapy. Journal of Geriatric Psychiatry and Neurology. 2004 Mar;17(1):42-6. [Abstract]

O'Connor MK. Electronic Medical Records and Depression Screening in Primary Care. Primary Care Companion to the Journal of Clinical Psychiatry. 2003 Aug;5(4):186. [No Abstract Available]

Cox LS, Patten CA, Krahn LE, Hurt RD, Croghan IT, Wolter TD, Schroeder DR, Tri D, Offord KP. The effect of nicotine patch therapy on depression in nonsmokers: a preliminary study. Journal of Addictive Diseases. 2003;22(4):75-85. [Abstract]

Lapid MI, Rummans TA. Evaluation and management of geriatric depression in primary care. Mayo Clinic Proceedings. 2003 Nov;78(11):1423-9. Review. [Abstract]

Vickers KS, Patten CA, Lane K, Clark MM, Croghan IT, Schroeder DR, Hurt RD. Depressed versus nondepressed young adult tobacco users: differences in coping style, weight concerns and exercise level. Health Psychology. 2003 Sep;22(5):498-503. [Abstract]

Reiff MI, Stein MT. Attention-deficit/hyperactivity disorder evaluation and diagnosis: a practical approach in office practice. Pediatric Clinics of North America. 2003 Oct;50(5):1019-48. Review. [Abstract]

Richelson E. Interactions of antidepressants with neurotransmitter transporters and receptors and their clinical relevance. Journal of Clinical Psychiatry. 2003;64 Suppl 13:5-12. Review. [Abstract]

Mahmud FH, Lteif AN, Renaud DL, Reed AM, Brands CK. Steroid-responsive encephalopathy associated with Hashimoto's thyroiditis in an adolescent with chronic hallucinations and depression: case report and review. Pediatrics. 2003 Sep;112(3 Pt 1):686-90. Review. [No Abstract Available]

Abramowitz JS, Whiteside S, Lynam D, Kalsy S. Is thought-action fusion specific to obsessive-compulsive disorder?: a mediating role of negative affect. Behaviour Research and Therapy. 2003 Sep;41(9):1069-79. [Abstract]

Mrazek DA. Psychiatric symptoms in patients with asthma causality, comorbidity, or shared genetic etiology. Child and Adolescent Psychiatric Clinics of North America. 2003 Jul;12(3):459-71. Review. [Abstract]

Thomas J, Jones G, Scarinci I, Brantley P. A descriptive and comparative study of the prevalence of depressive and anxiety disorders in low-income adults with type 2 diabetes and other chronic illnesses. Diabetes Care. 2003 Aug;26(8):2311-7. [Abstract]

Abramowitz JS, Schwartz SA, Moore KM, Luenzmann KR. Obsessive-compulsive symptoms in pregnancy and the puerperium: a review of the literature. Journal of Anxiety Disorders. 2003;17(4):461-78. Review. [Abstract]

Rasmussen KG. Clinical applications of recent research on electroconvulsive therapy. Bulletin of the Menninger Clinic. 2003 Winter;67(1):18-31. Review. [Abstract]

Rasmussen KG Jr, Russell JC, Kung S, Rummans TA, Rae-Stuart E, O'Connor MK. Electroconvulsive therapy for patients with major depression and probable Lewy body dementia. Journal of ECT. 2003 Jun;19(2):103-9. [Abstract]

Lapid MI, Rummans TA, Poole KL, Pankratz VS, Maurer MS, Rasmussen KG, Philbrick KL, Appelbaum PS. Decisional capacity of severely depressed patients requiring electroconvulsive therapy. Journal of ECT. 2003 Jun;19(2):67-72. [Abstract]

Patten CA, Vickers KS, Martin JE, Williams CD. Exercise interventions for smokers with a history of alcoholism: exercise adherence rates and effect of depression on adherence. Addictive Behaviors. 2003 Jun;28(4):657-67. [Abstract]

Benrud-Larson LM, Heinberg LJ, Boling C, Reed J, White B, Wigley FM, Haythornthwaite JA. Body image dissatisfaction among women with scleroderma: extent and relationship to psychosocial function. Health Psychology. 2003 Mar;22(2):130-9. [Abstract]

Caviness JN, Evidente VG. Cortical myoclonus during lithium exposure. Archives of Neurology. 2003 Mar;60(3):401-4. [Abstract]

Patten CA, Hurt RD, Offord KP, Croghan IT, Gomez-Dahl LC, Kottke TE, Morse RM, Joseph Melton L. Relationship of tobacco use to depressive disorders and suicidality among patients treated for alcohol dependence. American Journal on Addictions. 2003 Jan-Feb;12(1):71-83. [Abstract]

Russell JC, Rasmussen KG, O'Connor MK, Copeman CA, Ryan DA, Rummans TA. Long-term maintenance ECT: a retrospective review of efficacy and cognitive outcome. Journal of ECT. 2003 Mar;19(1):4-9. [Abstract]

Patten CA. Treating alcoholic smokers who have a history of depression. Alcoholism: Clinical and Experimental Research. 2002 Dec;26(12):1947-9. [No Abstract Available]

Perez-Jara J, Lucia E, Mayo F, Leon JJ, Alvarez J, Frei F, Enguix A. Non diagnosed depression among the institutionalized population in a rural area. International Journal of Geriatric Psychiatry. 2002 Oct;17(10):974-5. [No Abstract Available]

Rouge-Pont F, Mayo W, Marinelli M, Gingras M, Le Moal M, Piazza PV. The neurosteroid allopregnanolone increases dopamine release and dopaminergic response to morphine in the rat nucleus accumbens. European Journal of Neuroscience. 2002 Jul;16(1):169-73. [Abstract]

Camilleri M, Atanasova E, Carlson PJ, Ahmad U, Kim HJ, Viramontes BE, McKinzie S, Urrutia R. Serotonin-transporter polymorphism pharmacogenetics in diarrhea-predominant irritable bowel syndrome. Gastroenterology. 2002 Aug;123(2):425-32. [Abstract]

Patten CA, Drews AA, Myers MG, Martin JE, Wolter TD. Effect of depressive symptoms on smoking abstinence and treatment adherence among smokers with a history of alcohol dependence. Psychology of Addictive Behaviors. 2002 Jun;16(2):135-42. [Abstract]

Tucker S, Brust S, Richardson B. Validity of the depression coping self-efficacy scale. Archives of Psychiatric Nursing. 2002 Jun;16(3):125-33. [Abstract]

Tsuboi Y, Wszolek ZK, Kusuhara T, Doh-ura K, Yamada T. Japanese family with parkinsonism, depression, weight loss, and central hypoventilation. Neurology. 2002 Apr 9;58(7):1025-30. [Abstract]

Benrud-Larson LM, Haythornthwaite JA, Heinberg LJ, Boling C, Reed J, White B, Wigley FM. The impact of pain and symptoms of depression in scleroderma. Pain. 2002 Feb;95(3):267-75. [Abstract]

Sampson SM, Mrazek DA. Depression in adolescence. Current Opinion in Pediatrics. 2001 Dec;13(6):586-90. Review. [Abstract]