Depression

Clinical Trials

Below is a list of Depression clinical trials from the clinical trials database at Mayo Clinic.

Mayo's clinical trials include experimental treatments, often unavailable elsewhere, which frequently lead to improved patient care for people worldwide. Patients should ask their doctor at Mayo about clinical trials appropriate for their situation.

Investigation of Repetitive Transcranial Magnetic Stimulation in Depressed Adolescents
This research proposal aims to better understand the neurobiology of depression in adolescents and how repetitive transcranial magnetic stimulation (rTMS) may therapeutically impact brain function and mood. This research will be the first study evaluating metabolic changes in the brain as a result of rTMS treatment in depressed adolescents using magnetic resonance spectroscopy (MRS).
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Ketamine Anesthesia in Electroconvulsive Therapy
To compare outcomes with electroconvulsive therapy using ketamine or methohexital as anesthetic.
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Pharmacodynamics and Pharmacokinetics of Citalopram and Escitalopram
This study is one component of a larger U01 grant that was submitted in August, 2004 to the NIGMS as part of the Pharmacogenomic Research Network. This study will enroll 1200 patients over 4 years.
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Prolonging Remission in Depressed Elderly (PRIDE)
While advances have been made in the acute treatment of geriatric depression, failure to maintain remission following successful treatment remains a major public health problem. In particular, loss of antidepressant response can result in ongoing functional impairment and increased risk of suicide.
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