Mayo Clinic works with hundreds of insurance companies and is an in-network provider for millions of people. In most cases, Mayo Clinic doesn't require a physician referral. Some insurers require referrals, or may have additional requirements for certain medical care. All appointments are prioritized on the basis of medical need.

Online Requests

Telephone Requests

U.S. Patients


Call the Central Appointment Office
800-446-2279 (toll-free)
8 a.m. to 5 p.m. Mountain Standard Time, Monday through Friday


Call Radiation Oncology
8 a.m. to 5 p.m. Eastern time, Monday through Friday


Call Radiation Oncology
8 a.m. to 5 p.m. Central time, Monday through Friday

International Patients

Please refer to the international appointment section to request appointments via phone.

Becoming a Patient

See information on patient services at the three Mayo Clinic locations, including transportation options and lodging.