Below are current clinical trials.8 studies in Otorhinolaryngology (ENT) in Arizona
(open studies only).
Filter this list of studies by location, status and more.
Visually Evoked Potentials (VEPs) are electrical potentials elicited from brief visual stimuli and recorded from the visual cortex with surface electrodes. VEPs are an objective, reliable, and non-invasive method for evaluation of the functional integrity of the retina and early afferent visual pathways. The purpose of this study is to compare the VEPs generated from a standard clinical evoked potential system to those obtained from the Vivonics portable VEP system.
The goals of the study are to develop protocols for growing cells isolated from the nasal epithelium and fat tissue. This will be used to help grow nerve-related tissue as well as cartilage, epithelial cells, muscle cells, or other cells that are present in the head and neck region. The goal is to generate a large number of cells that could be used for constructing tissue that can be implanted for structural and functional reconstruction.
The development of such methods is a step in our goal to rehabilitate patients with cancer, trauma, or other debilitating neurological diseases that lose function and structure in the head and neck area. The cells isolated from your tissues will not be used for developing implants but will help with experiments to establish the protocols needed to cultivate cells and develop the implant.
Muscle tension dysphagia is a novel diagnostic taxonomy describing a subset of patient population with reported dysphagia who exhibit normal oropharyngeal and esophageal swallowing function as evidenced by videofluoroscopic swallow study. These patients also demonstrate abnormal supraglottic muscle tension during laryngoscopy as well as signs of laryngeal hypersensitivity and laryngopharyngeal reflux. Treatment of these patients with Proton Pump Inhibitor (PPI) therapy is a common practice however voice therapy invention targeting the unloading of the supraglottic muscle tension has been shown to be highly effective in symptom resolution per the investigators' clinical experience. The study is designed to answer efficacy of treatment being offered to patients with muscle tension dysphagia.
To evaluate the efficacy of dupilumab compared to placebo on a background of mometasone furoate nasal spray (MFNS) in reducing nasal congestion/obstruction (NC) severity and endoscopic nasal polyposis score (NPS) in patients with bilateral nasal polyposis (NP). In addition for Japan, reduction in computed tomography (CT) scan opacification of the sinuses will be also a co-primary objective.
- To evaluate the efficacy of dupilumab in improving total symptoms score (TSS).
- To evaluate the efficacy of dupilumab in improving sense of smell.
- To evaluate the efficacy of dupilumab in reducing CT scan opacification of the sinuses (Primary objective for Japan).
- To evaluate ability of dupilumab in reducing proportion of patients requiring treatment with oral corticosteroids or NP surgery.
- To evaluate the effect of dupilumab on patient reported outcomes and health related quality of life outcome by sinonasal outcome test-22 (SNOT-22).
- To evaluate efficacy with various regimen.
- To evaluate the effect of dupilumab in the subgroups of patients with prior surgery and co-morbid asthma (including non-steroid antiinflammatory drug [NSAID] exacerbated respiratory disease [NERD]).
- To evaluate the safety of dupilumab in patients with bilateral NP.
- To evaluate functional dupilumab concentrations (systemic exposure) and incidence of treatment-emergent anti-drug antibodies (ADA).
The purpose of this study is to develop the procedures for the growth of specific cells and tissues needed for reconstruction surgeries of the head and neck using the waste tissues of other surgeries.
The specific aim of this work is to optimize consumer and non-physician detection of ear disease.
The purpose of this study is to screen for unique or characteristic circulating peptides, hormonal biomarkers and circulating mRNA in patients who have experienced spontaneous coronary artery dissection (SCAD).
Scottsdale/Phoenix, Ariz., Rochester, Minn.
In patients with gastroesophageal reflux and/or laryngopharyngeal reflux with cricopharyngeal hypertrophy or Zenker's diverticulum, does cricopharyngeal myotomy increase the amount of laryngopharyngeal reflux?