Reproductive Endocrinology and Infertility

Mayo Clinic's Division of Reproductive Endocrinology and Infertility manages complex fertility problems, including:

  • Unexplained infertility
  • Male factor infertility, such as significant problems with sperm quality or prior vasectomy
  • Third-party reproduction, including gestational carriers, sperm donors, egg donors or a combination of these
  • Fertility preservation
  • Deferred reproduction
  • Recurrent pregnancy loss
  • Risk of genetic disorders in offspring
  • Amenorrhea
  • Endometriosis
  • Polycystic ovary disease
  • Primary ovarian insufficiency (formerly called premature ovarian failure)
  • Congenital uterine disorders

Mayo Clinic specialists offer an integrated approach to diagnosis and treatment, which may include evaluation by doctors in other specialties and comprehensive diagnostic testing and counseling. All of our staff physicians are board certified in obstetrics and gynecology as well as reproductive endocrinology and infertility.

Fertility preservation

Fertility preservation services offered include:

  • Freezing of unfertilized eggs (oocyte cryopreservation)
  • Freezing of fertilized eggs (embryo cryopreservation)
  • Freezing of ovarian tissue (ovarian tissue cryopreservation)
  • Freezing of sperm (sperm cryopreservation)

Reproductive surgery

Many gynecologic surgeries can reduce your fertility. Mayo Clinic reproductive endocrinology and infertility doctors specialize in gynecologic surgeries that optimize or maintain your maximum fertility potential.

Specialists in this area use minimally invasive and open approaches to treat:

Mayo Clinic specialists optimize fertility by carefully handling tissue and, where appropriate, using adhesion barriers to decrease formation of scar tissue. They also perform outpatient microsurgical reversal of tubal ligations and offer fertility optimization services to women needing surgery on their ovaries.

Success rates

The success of fertility services offered at Mayo Clinic results from the combined efforts of a team dedicated to providing care with compassion, expertise and innovation.

Understandably, if you're seeking fertility services, you would like some assurance that you are choosing a successful program. Keep in mind that success rates differ due to a variety of individual factors. Your reproductive endocrinologist can best help you evaluate the chances of success in your personal situation.

Web resources

Society for Assisted Reproductive Technology: What are my chances with ART?

Mayo Clinic’s success rates

Society for Assisted Reproductive Technology: Clinical summary report

Success rates for in vitro fertilization (IVF) programs are readily available to the public. When choosing a fertility service provider, you may be tempted to compare programs based on success rates. However, many clinics and IVF programs publish success rates even though the Centers for Disease Control and Prevention and the Society for Assisted Reproductive Technology (SART) recognize that direct comparisons between clinics aren't possible:

  • Different clinics have different patient populations and practice styles.
  • Programs vary greatly in the screening process for patients prior to an IVF cycle and may not be willing to care for a patient with a particularly challenging history or medical condition.

Embryo development technology

At Mayo Clinic, fertility specialists provide high-quality care through expertise, attention to detail and innovation. Time-lapse imaging of embryo development is one example of an innovative technology that Mayo Clinic fertility specialists have adopted to provide patients with the very best outcomes.

LGBT services

Many individuals in the lesbian, gay, bisexual and transgender (LGBT) community face unique challenges in building a family.

The Mayo Clinic Assisted Reproductive Technology Program enthusiastically supports the reproductive needs of this community by offering a variety of reproductive services that enable family building, including:

  • Donor sperm insemination
  • Donor egg
  • Gestational carrier cycles
  • Use of both a gestational carrier and an egg donor

The first step is to schedule a consultation with one of the providers in the Division of Reproductive Endocrinology and Infertility to discuss the available options and to make a plan that fits your specific needs.


You may be referred to the Division of Reproductive Endocrinology and Infertility by your primary doctor, or you may request an appointment without a referral.

For appointments or more information about fertility services at Mayo Clinic's campus in Minnesota, call the Division of Reproductive Endocrinology and Infertility at 507-284-9792 from 8 a.m. to 5 p.m., Monday through Friday, or complete an online appointment request form.

See health care staff.