Clinical Core Laboratory Services

By Mayo Clinic Staff

The Division of Clinical Core Laboratory Services is a diverse group of 10 "laboratories" dedicated primarily to the support of the Mayo Clinic practice in Minnesota. Its activities include specimen collection, processing, analysis and reporting for approximately 8.9 million procedures annually. Six doctoral-level lab directors and more than 600 allied health staff work in the division.

The following groups are part of the Division:

Laboratory Services (Phlebotomy)
Laboratory Services consists of four locations on the Rochester campus that are dedicated to the collection of specimens for Mayo patients. They provide services to the inpatients of Mayo Clinic Hospital, Saint Marys Campus and Mayo Clinic Hospital, Methodist Campus, outpatients from Mayo's primary and specialty care practices, pediatrics patients, nursing home patients, and Mayo employees. Services include blood collection; provision of containers for urine, sputum and stool samples; blood glucose and pH testing; tuberculin testing; bleeding times; sweat and breath collection. Together with the Vascular Access Service and the Hospital Clinical Laboratory, approximately one million collection-related procedures are performed each year.

Vascular Access Services
The Vascular Access Team is a group of specialized technicians dedicated to six Intensive Care Units at Mayo Clinic Hospital, Saint Marys Campus. Continuous service is provided to patients who are critically ill as a result of trauma, surgery, cardiac disease, neurologic disease or other significant medical conditions. Technicians perform insertion of intravenous catheters; venous, capillary and arterial blood collection through vascular puncture; arterial and venous blood collection from peripheral or central intravascular lines; and point-of-care testing for glucose, hemoglobin, blood gases and coagulation.

Specimen Collection Facility
The Specimen Collection Facility provides patient instruction for self-collection of multiple specimen types as well as processing support for the Department of Laboratory Medicine.

Central Processing
Central Processing receives, triages, and processes all blood and body fluid specimens from throughout the Mayo Rochester campus, as well as from Mayo Medical Laboratories and other satellite laboratories in the local area.

Hospital Clinical Laboratories
The Hospital Clinical Laboratories are a group of laboratories dedicated to the provision of rapid laboratory testing for Mayo patients. The laboratories located at Mayo Clinic Hospital, Saint Marys Campus and Mayo Clinic Hospital, Methodist Campus perform a limited menu of tests in a 15- to 45-minute time frame; these tests include blood gases, electrolytes, blood cell counts, coagulation times, cardiac markers, and simple urinalysis. The results are provided primarily to the operating rooms, emergency department, intensive care units and the code team for medical emergencies where fast results are needed for acute care. The Point of Care Testing program is managed through these laboratories. Satellite laboratories supporting Mayo's local primary care clinics are part of this group as well.

Central Clinical Laboratory
The Central Clinical Laboratory (CCL) is a highly automated, high-volume core laboratory which provides testing for Mayo Clinic Hospital, Methodist Campus and Mayo Clinic Hospital, Saint Marys Campus, Mayo Clinic outpatients, Mayo Medical Laboratories, and Clinical Trials clients. The CCL provides STAT and routine testing for automated chemistry, automated hematology and immunoassay determinations. The CCL performs over 4 million tests per year which accounts for about 40 percent of the testing volume of Department of Laboratory Medicine and Pathology. The CCL staff actively participates in research studies related to the development of new clinical tests, the clinical utility and outcomes assessment of those tests, and appropriate test use.

Renal Laboratory
The Renal Laboratory is a testing and diagnostic lab that performs renal function testing and urinalysis. It is a high-volume lab that provides STAT and routine testing for Mayo Clinic Hospital, Saint Marys Campus and Mayo Clinic Hospital, Methodist Campus, Mayo Clinic outpatients, Mayo Medical Laboratories, and Clinical Trial clients. One unique feature of the Renal Lab is that it contains both an analytical lab utilizing technical staff and a patient testing unit employing nursing staff. The Renal Lab averages about 10,000 urinalysis and 5,000 gram stains per month, with a good percentage of these tests performed manually. Other types of methodologies used in the Renal Lab include capillary electrophoresis, HPLC, wet chemistries, and auto analyzer. The Renal Lab provides testing for research and is actively developing new tests for renal function assessment.