Calciphylaxis is a serious condition in which abnormal amounts of calcium are deposited in the body, mainly in the small blood vessels that supply fat tissue (vascular calcification). The cause of calciphylaxis is unknown, but doctors believe that an imbalance in the metabolism of calcium causes calcium to be deposited in the smallest parts of the arteries (arterioles). This eventually leads to the formation of blood clots in the arterioles, depriving the fat and skin above it from oxygen and nourishment.
Calciphylaxis most commonly affects people who have end-stage kidney failure. Risk factors include:
Rarely, calciphylaxis occurs in people with no known kidney or calcium abnormalities for unknown reasons.
If you have this disease, you will often have:
Complications of calciphylaxis include:
Typically, the outlook for people with calciphylaxis is not good, so early detection and treatment is very important.